Shiloh
Editor, Senior Moderator
Source: http://7thspace.com/headlines/36417...sification_rates_and_population_dynamics.html
Evolution of Dengue Virus type 3 genotype III in Venezuela: diversification, rates and population dynamics.
Dengue virus (DENV) is a member of the genus Flavivirus of the family Flaviviridae. DENV are comprised of four distinct serotypes (DENV-1 through DENV-4) and each serotype can be divided in different genotypes.
Currently, there is a dramatic emergence of DENV-3 genotype III in Latin America. Nevertheless, we still have an incomplete understanding of the evolutionary forces underlying the evolution of this genotype in this region of the world...
...Conclusions: A significant evolutionary change between DENV-3 genotype III strains that circulated in the initial years of the introduction in the continent and strains isolated in the Latin American region in recent years was observed. The presence of DENV-3 genotype III strains belonging to different clusters was observed in Venezuela, revealing several introduction events into this country.
The evolutionary rate found for Cluster A strains circulating in Venezuela is similar to the others previously established for this genotype in other regions of the world. This suggests a lack of correlation among DENV genotype III substitution rate and ecological pattern of virus spread.
Author: Alvaro RamirezAlvaro FajardoZoila MorosMarlene GerderGerson CaraballoDaria CamachoGuillermo ComachVictor AlarconJulio ZambranoRosa HernandezGonzalo MoratorioJuan CristinaFerdinando Liprandi
Credits/Source: Virology Journal 2010, 7:329
Evolution of Dengue Virus type 3 genotype III in Venezuela: diversification, rates and population dynamics.
Dengue virus (DENV) is a member of the genus Flavivirus of the family Flaviviridae. DENV are comprised of four distinct serotypes (DENV-1 through DENV-4) and each serotype can be divided in different genotypes.
Currently, there is a dramatic emergence of DENV-3 genotype III in Latin America. Nevertheless, we still have an incomplete understanding of the evolutionary forces underlying the evolution of this genotype in this region of the world...
...Conclusions: A significant evolutionary change between DENV-3 genotype III strains that circulated in the initial years of the introduction in the continent and strains isolated in the Latin American region in recent years was observed. The presence of DENV-3 genotype III strains belonging to different clusters was observed in Venezuela, revealing several introduction events into this country.
The evolutionary rate found for Cluster A strains circulating in Venezuela is similar to the others previously established for this genotype in other regions of the world. This suggests a lack of correlation among DENV genotype III substitution rate and ecological pattern of virus spread.
Author: Alvaro RamirezAlvaro FajardoZoila MorosMarlene GerderGerson CaraballoDaria CamachoGuillermo ComachVictor AlarconJulio ZambranoRosa HernandezGonzalo MoratorioJuan CristinaFerdinando Liprandi
Credits/Source: Virology Journal 2010, 7:329