tetano
Editor, Senior Moderator
Epidemiol Infect. 2014 Jun 13:1-10. [Epub ahead of print]
Extended transmission of two H5/H7 low pathogenic avian influenza viruses in chickens.
Claes G1, Lambrecht B1, Dewulf J2, van den Berg T1, March? S1.
Author information
Abstract
SUMMARY Transmission experiments are useful for investigating the mechanisms of low pathogenic notifiable avian influenza virus (LPNAI) transmission. In this study, the hypothesis that inoculation-infected chickens are more infectious than contact-infected chickens was tested. To this end, extended transmission experiments with one H5N2 and one H7N1 LPAIV which had previously been characterized in a series of standard transmission experiments were conducted in specific pathogen-free (SPF) chickens. For the H5N2 LPAIV, the infectivity of contact-infected chickens was similar to the infectivity of inoculated chickens. Despite results from a previous study suggesting the H7N1 LPAIV strain to be similarly infectious to SPF chickens as the H5N2 LPAIV strain, the acquisition of contact-infected chickens proved more difficult for H7N1 LPAIV. It was assumed that this might have been a consequence of the length and timing of the exposure period. In conclusion, for LPNAIVs that first seemed equally infectious, short-term transmissibility may vary considerably.
PMID:
24924291
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24924291
Extended transmission of two H5/H7 low pathogenic avian influenza viruses in chickens.
Claes G1, Lambrecht B1, Dewulf J2, van den Berg T1, March? S1.
Author information
Abstract
SUMMARY Transmission experiments are useful for investigating the mechanisms of low pathogenic notifiable avian influenza virus (LPNAI) transmission. In this study, the hypothesis that inoculation-infected chickens are more infectious than contact-infected chickens was tested. To this end, extended transmission experiments with one H5N2 and one H7N1 LPAIV which had previously been characterized in a series of standard transmission experiments were conducted in specific pathogen-free (SPF) chickens. For the H5N2 LPAIV, the infectivity of contact-infected chickens was similar to the infectivity of inoculated chickens. Despite results from a previous study suggesting the H7N1 LPAIV strain to be similarly infectious to SPF chickens as the H5N2 LPAIV strain, the acquisition of contact-infected chickens proved more difficult for H7N1 LPAIV. It was assumed that this might have been a consequence of the length and timing of the exposure period. In conclusion, for LPNAIVs that first seemed equally infectious, short-term transmissibility may vary considerably.
PMID:
24924291
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24924291