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F1000Res . Emerging threat and vaccination strategies of H9N2 viruses in poultry in Indonesia: A review

tetano

Editor, Senior Moderator
F1000Res


. 2022 May 19;11:548.
doi: 10.12688/f1000research.118669.1. eCollection 2022.
Emerging threat and vaccination strategies of H9N2 viruses in poultry in Indonesia: A review


Saifur Rehman[SUP] 1 2 3 [/SUP], Fedik Abdul Rantam[SUP] 2 [/SUP], Khadija Batool[SUP] 4 [/SUP], Aamir Shehzad[SUP] 2 [/SUP], Mustofa Helmi Effendi[SUP] 1 [/SUP], Adiana Mutamsari Witaningrum[SUP] 1 [/SUP], Muhammad Bilal[SUP] 3 [/SUP], Muhammad Thohawi Elziyad Purnama[SUP] 5 [/SUP]



Affiliations
Free PMC article

Abstract

Avian influenza virus subtype H9N2 was first documented in Indonesia in 2017. It has become prevalent in chickens in many provinces of Indonesia as a result of reassortment in live bird markets. Low pathogenic avian influenza subtype H9N2 virus-infected poultry provides a new direction for influenza virus. According to the latest research, the Indonesian H9N2 viruses may have developed through antigenic drift into new genotype, posing a significant hazard to poultry and public health. The latest proof of interspecies transmission proposes that, the next human pandemic variant will be avian influenza virus subtype H9N2. Manipulation and elimination of H9N2 viruses in Indonesia, constant surveillance of viral mutation, and vaccines updates are required to achieve effectiveness. The current review examines should be investigates/assesses/report on the development and evolution of newly identified H9N2 viruses in Indonesia and their vaccination strategy.

Keywords: Indonesia; avian influenza; emergence; public health; vaccination.
 
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