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Factors Associated With Influenza in an Emergency Department Setting

tetano

Editor, Senior Moderator
J Emerg Med. 2019 Feb 22. pii: S0736-4679(18)31203-4. doi: 10.1016/j.jemermed.2018.12.012. [Epub ahead of print]
[h=1]Factors Associated With Influenza in an Emergency Department Setting.[/h] Pedersen CJ[SUP]1[/SUP], Quinn JV[SUP]2[/SUP], Rogan DT[SUP]2[/SUP], Yang S[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Emergency departments (EDs) become more overcrowded during peak respiratory virus season. Distinguishing influenza from other viruses is crucial to implement social distancing practices, early treatment, and prompt disposition.
[h=4]OBJECTIVES:[/h] We sought to determine factors associated with influenza among a prospective cohort of consecutive ED patients with acute respiratory illness (ARI).
[h=4]METHODS:[/h] Between December 2016 and March 2017, trained research assistants screened consecutive ED patients with ARI symptoms. ARI criteria included measured fever at home or in the ED >38?C and a cough, sore throat, or rhinorrhea with a duration of symptoms >12 hours and <1 week. After consent, research assistants collected demographics and clinical history using a standardized data form, and patients had a polymerase chain reaction-based assay that is nearly 100% sensitive for influenza. Univariate analysis was conducted on all predictor variables. Significant variables were entered into a multivariate logistic regression model to find factors that were independently associated with influenza.
[h=4]RESULTS:[/h] One hundred nineteen patients consented to enrollment and 31% were found to be positive for influenza. Myalgia, the absence of gastrointestinal symptoms (no diarrhea or vomiting), sore throat, chills, headache, and oxygen saturation ≥97% were significant on univariate analysis and were entered into the multivariate model. Myalgia (adjusted odds ratio [AOR] 3.9), the absence of gastrointestinal symptoms (AOR 4.7), and oxygen saturation ≥97% (AOR 2.8) were significant independent factors of influenza.
[h=4]CONCLUSION:[/h] The presence of myalgia, the absence of gastrointestinal symptoms, and oxygen saturation ≥97% are factors that can help distinguish influenza from other acute respiratory illnesses in the ambulatory ED population.
Copyright ? 2018 Elsevier Inc. All rights reserved.


[h=4]KEYWORDS:[/h] acute respiratory illness; influenza; nosocomial infections; predictors

PMID: 30803847 DOI: 10.1016/j.jemermed.2018.12.012
 
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