tetano
Editor, Senior Moderator
Gastroenterol Hepatol Bed Bench
. Fall 2021;14(Suppl1):S24-S31.
Gut microbiota, angiotensin-converting enzyme, celiac disease, and risk of COVID-19 infection: a review
Fahimeh Sadat Gholam-Mostafaei[SUP] 1 [/SUP], Tina Didari[SUP] 2 3 [/SUP], Marzieh Ramandi[SUP] 4 [/SUP], Reza Vafaee[SUP] 5 [/SUP], Mohammad Rostami-Nejad[SUP] 1 [/SUP]
Affiliations
Abstract
Celiac disease (CD) is an autoimmune disorder of the gastrointestinal tract in a genetically susceptible person. Gluten is the most crucial trigger factor for CD, and environmental factors such as microbiota and opportunistic infection risk its pathogenesis. Coronavirus disease 19 (COVID-19) spread rapidly and became a problem for healthcare systems worldwide. Little is known about the risk of severe COVID-19 and the role of dysbiosis among patients with CD. There is also a lack of knowledge about the effects of CD gut microbiota on COVID-19 infection. Therefore, the current review discusses the relationship between CD and risk factors such as microbiota for susceptibility to COVID-19.
Keywords: ACE2 receptor; COVID-19; Celiac disease; Gut microbiota; SARS-CoV-2.
. Fall 2021;14(Suppl1):S24-S31.
Gut microbiota, angiotensin-converting enzyme, celiac disease, and risk of COVID-19 infection: a review
Fahimeh Sadat Gholam-Mostafaei[SUP] 1 [/SUP], Tina Didari[SUP] 2 3 [/SUP], Marzieh Ramandi[SUP] 4 [/SUP], Reza Vafaee[SUP] 5 [/SUP], Mohammad Rostami-Nejad[SUP] 1 [/SUP]
Affiliations
- PMID: 35154599
- PMCID: PMC8817746
Abstract
Celiac disease (CD) is an autoimmune disorder of the gastrointestinal tract in a genetically susceptible person. Gluten is the most crucial trigger factor for CD, and environmental factors such as microbiota and opportunistic infection risk its pathogenesis. Coronavirus disease 19 (COVID-19) spread rapidly and became a problem for healthcare systems worldwide. Little is known about the risk of severe COVID-19 and the role of dysbiosis among patients with CD. There is also a lack of knowledge about the effects of CD gut microbiota on COVID-19 infection. Therefore, the current review discusses the relationship between CD and risk factors such as microbiota for susceptibility to COVID-19.
Keywords: ACE2 receptor; COVID-19; Celiac disease; Gut microbiota; SARS-CoV-2.