tetano
Editor, Senior Moderator
Gene
. 2022 Mar 3;146387.
doi: 10.1016/j.gene.2022.146387. Online ahead of print.
Role of Genomics in combating COVID-19 pandemic
K A Saravanan[SUP] 1 [/SUP], Manjit Panigrahi[SUP] 2 [/SUP], Harshit Kumar[SUP] 1 [/SUP], Divya Rajawat[SUP] 1 [/SUP], Sonali Sonejita Nayak[SUP] 1 [/SUP], Bharat Bhushan[SUP] 1 [/SUP], Triveni Dutt[SUP] 3 [/SUP]
Affiliations
Abstract
The coronavirus disease 2019 (COVID-19) quickly swept over the world, becoming one of the most devastating outbreaks in human history. Being the first pandemic in the post-genomic era, advancements in genomics contributed significantly to scientific understanding and public health response to COVID-19. Genomic technologies have been employed by researchers all over the world to better understand the biology of SARS-CoV-2 and its origin, genomic diversity, and evolution. Worldwide genomic resources have greatly aided in the investigation of the COVID-19 pandemic. The pandemic has ushered in a new era of genomic surveillance, wherein scientists are tracking the changes of the SARS-CoV-2 genome in real-time at the international and national levels. Availability of genomic and proteomic information enables the rapid development of molecular diagnostics and therapeutics. The advent of high-throughput sequencing and genome editing technologies led to the development of modern vaccines. We briefly discuss the impact of genomics in the ongoing COVID-19 pandemic in this review.
Keywords: COVID-19; Genomic surveillance; Genomics; Reverse vaccinology; SARS-CoV-2.
. 2022 Mar 3;146387.
doi: 10.1016/j.gene.2022.146387. Online ahead of print.
Role of Genomics in combating COVID-19 pandemic
K A Saravanan[SUP] 1 [/SUP], Manjit Panigrahi[SUP] 2 [/SUP], Harshit Kumar[SUP] 1 [/SUP], Divya Rajawat[SUP] 1 [/SUP], Sonali Sonejita Nayak[SUP] 1 [/SUP], Bharat Bhushan[SUP] 1 [/SUP], Triveni Dutt[SUP] 3 [/SUP]
Affiliations
- PMID: 35248659
- DOI: 10.1016/j.gene.2022.146387
Abstract
The coronavirus disease 2019 (COVID-19) quickly swept over the world, becoming one of the most devastating outbreaks in human history. Being the first pandemic in the post-genomic era, advancements in genomics contributed significantly to scientific understanding and public health response to COVID-19. Genomic technologies have been employed by researchers all over the world to better understand the biology of SARS-CoV-2 and its origin, genomic diversity, and evolution. Worldwide genomic resources have greatly aided in the investigation of the COVID-19 pandemic. The pandemic has ushered in a new era of genomic surveillance, wherein scientists are tracking the changes of the SARS-CoV-2 genome in real-time at the international and national levels. Availability of genomic and proteomic information enables the rapid development of molecular diagnostics and therapeutics. The advent of high-throughput sequencing and genome editing technologies led to the development of modern vaccines. We briefly discuss the impact of genomics in the ongoing COVID-19 pandemic in this review.
Keywords: COVID-19; Genomic surveillance; Genomics; Reverse vaccinology; SARS-CoV-2.