tetano
Editor, Senior Moderator
Sci Rep. 2015 Dec 2;5:17508. doi: 10.1038/srep17508.
[h=1]Genetic and molecular characterization of H9N2 and H5 avian influenza viruses from live poultry markets in Zhejiang Province, eastern China.[/h] Wu H[SUP]1[/SUP], Peng X[SUP]1[/SUP], Peng X[SUP]1[/SUP], Cheng L[SUP]1[/SUP], Lu X[SUP]1[/SUP], Jin C[SUP]1[/SUP], Xie T[SUP]1[/SUP], Yao H[SUP]1[/SUP], Wu N[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Live poultry markets (LPMs) are a key source of reassorted avian influenza viruses (AIVs) because of the density of terrestrial and aquatic poultry and the frequency of AIV infection. H9N2 viruses are prevalent in terrestrial poultry throughout Asia and have been isolated from poultry outbreaks worldwide. They infect both avian and mammalian species and may be significant donors of genetic material to emerging human pathogens. LPMs in Zhejiang Province were surveyed from 2013-2014 for AIVs. Three hundred seventy-four (374) AIV strains were isolated from 3,328 samples. Whole-genome sequencing and phylogenetic analyses were performed. We identified a novel H9N2 virus genotype that had undergone reassortment with gene segments from Qa/HK/G1/97-like, Ck/BJ/1/94-like, and Dk/HK/Y439/97-like viruses. Phylogenetic analyses suggested the H9N2 viruses had undergone reassortments with other AIV subtypes. The results also suggested that two different clades (2.3.2 and 2.3.4.6) of H5 viruses were co-circulating in Zhejiang Province. Given that reassorted H5 AIVs were detected in geese and ducks, it is possible that apparently healthy birds contribute to emerging H5 AIVs. Continued surveillance is required in poultry in eastern China.
PMID: 26627108 [PubMed - in process] Free full text
[h=1]Genetic and molecular characterization of H9N2 and H5 avian influenza viruses from live poultry markets in Zhejiang Province, eastern China.[/h] Wu H[SUP]1[/SUP], Peng X[SUP]1[/SUP], Peng X[SUP]1[/SUP], Cheng L[SUP]1[/SUP], Lu X[SUP]1[/SUP], Jin C[SUP]1[/SUP], Xie T[SUP]1[/SUP], Yao H[SUP]1[/SUP], Wu N[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Live poultry markets (LPMs) are a key source of reassorted avian influenza viruses (AIVs) because of the density of terrestrial and aquatic poultry and the frequency of AIV infection. H9N2 viruses are prevalent in terrestrial poultry throughout Asia and have been isolated from poultry outbreaks worldwide. They infect both avian and mammalian species and may be significant donors of genetic material to emerging human pathogens. LPMs in Zhejiang Province were surveyed from 2013-2014 for AIVs. Three hundred seventy-four (374) AIV strains were isolated from 3,328 samples. Whole-genome sequencing and phylogenetic analyses were performed. We identified a novel H9N2 virus genotype that had undergone reassortment with gene segments from Qa/HK/G1/97-like, Ck/BJ/1/94-like, and Dk/HK/Y439/97-like viruses. Phylogenetic analyses suggested the H9N2 viruses had undergone reassortments with other AIV subtypes. The results also suggested that two different clades (2.3.2 and 2.3.4.6) of H5 viruses were co-circulating in Zhejiang Province. Given that reassorted H5 AIVs were detected in geese and ducks, it is possible that apparently healthy birds contribute to emerging H5 AIVs. Continued surveillance is required in poultry in eastern China.
PMID: 26627108 [PubMed - in process] Free full text