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Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018

tetano

Editor, Senior Moderator
Emerg Infect Dis. 2019 Oct;25(10):1973-1976. doi: 10.3201/eid2510.181931.
[h=1]Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018.[/h] Pohlmann A, Hoffmann D, Grund C, Koethe S, H?ssy D, Meier SM, King J, Schink?the J, Ulrich R, Harder T, Beer M.
[h=3]Abstract[/h] We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment.


[h=4]KEYWORDS:[/h] Germany; H5N5; H5N6; H5N8; H5Nx; HPAI; clade 2.3.4.4b; epizootic; ferret model; highly pathogenic avian influenza; influenza; reassortment; respiratory infections; viruses; zoonoses; zoonotic potential

PMID: 31538926 DOI: 10.3201/eid2510.181931
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