tetano
Editor, Senior Moderator
Emerg Infect Dis. 2016 Dec 15;22(12). doi: 10.3201/eid2212.160578. [Epub ahead of print]
[h=1]Genetically Different Highly Pathogenic Avian Influenza A(H5N1) Viruses in West Africa, 2015.[/h] Tassoni L, Fusaro A, Milani A, Lemey P, Awuni JA, Sedor VB, Dogbey O, Commey AN, Meseko C, Joannis T, Minoungou GL, Ouattara L, Haido AM, Cisse-Aman D, Couacy-Hymann E, Dauphin G, Cattoli G, Monne I.
[h=3]Abstract[/h] To trace the evolution of highly pathogenic influenza A(H5N1) virus in West Africa, we sequenced genomes of 43 viruses collected during 2015 from poultry and wild birds in 5 countries. We found 2 co-circulating genetic groups within clade 2.3.2.1c. Mutations that may increase adaptation to mammals raise concern over possible risk for humans.
[h=4]KEYWORDS:[/h] Africa; H5N1 subtype; HPAI; Influenza A virus; West Africa; genetic groups; highly pathogenic avian influenza; phylogeny; respiratory infections; viruses
PMID: 27389972 DOI: 10.3201/eid2212.160578
[PubMed - as supplied by publisher] Free full text
[h=1]Genetically Different Highly Pathogenic Avian Influenza A(H5N1) Viruses in West Africa, 2015.[/h] Tassoni L, Fusaro A, Milani A, Lemey P, Awuni JA, Sedor VB, Dogbey O, Commey AN, Meseko C, Joannis T, Minoungou GL, Ouattara L, Haido AM, Cisse-Aman D, Couacy-Hymann E, Dauphin G, Cattoli G, Monne I.
[h=3]Abstract[/h] To trace the evolution of highly pathogenic influenza A(H5N1) virus in West Africa, we sequenced genomes of 43 viruses collected during 2015 from poultry and wild birds in 5 countries. We found 2 co-circulating genetic groups within clade 2.3.2.1c. Mutations that may increase adaptation to mammals raise concern over possible risk for humans.
[h=4]KEYWORDS:[/h] Africa; H5N1 subtype; HPAI; Influenza A virus; West Africa; genetic groups; highly pathogenic avian influenza; phylogeny; respiratory infections; viruses
PMID: 27389972 DOI: 10.3201/eid2212.160578
[PubMed - as supplied by publisher] Free full text