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Glycaemic control, antidiabetic medications and influenza vaccination coverage among patients with diabetes in Udine, Italy

tetano

Editor, Senior Moderator
Fam Med Community Health. 2019 Sep 6;7(3):e000198. doi: 10.1136/fmch-2019-000198. eCollection 2019. [h=1]Glycaemic control, antidiabetic medications and influenza vaccination coverage among patients with diabetes in Udine, Italy.[/h]
Valent F[SUP]1[/SUP], Tullio A[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]Objective:[/h] The objectives of this study were to estimate influenza vaccination coverage among patients with diabetes mellitus in an Italian 250 000-inhabitant area in the 2017-2018 season and to assess whether glycaemic control and pharmacological treatment were associated with the likelihood of being vaccinated.
[h=4]Design:[/h] In this cross-sectional study, we analysed anonymous health administrative databases, linked with each other at the individual patient level through a stochastic key: diabetes mellitus registry, vaccinations, drug prescriptions and laboratory database.
[h=4]Setting:[/h] The study was conducted in the catchment area of the University Hospital of Udine ('the Udine area'), a 250 000-inhabitant area in the northeast of Italy.
[h=4]Participants:[/h] The study included all subjects included in the regional registry of patients with diabetes mellitus, living in the Udine area as of 1 October 2017.
[h=4]Main outcome measures:[/h] Vaccination coverage in the 2017-2018 influenza season was calculated. The association between patients' characteristics and the likelihood of being vaccinated was assessed through multivariate log binomial regression.
[h=4]Result:[/h] 53.0% of 15 900 patients with diabetes living in the area were vaccinated. Coverage increased with age, approaching 75% at ≥85 years. Patients lacking recent glycated haemoglobin testing were less likely to be vaccinated (43.4% vaccination coverage), as were those not treated pharmacologically (44.4% vaccination coverage). Patients treated with both insulin, metformin and other antidiabetic medications were more likely to be vaccinated than those treated with metformin alone (58.1% vaccination coverage; adjusted relative risk=1.07, 95% CI 1.01 to 1.14).
[h=4]Conclusion:[/h] Influenza vaccination coverage was suboptimal in this Italian population of patients with diabetes. Strategies to improve diabetes management could in turn positively affect influenza coverage.
? Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.


[h=4]KEYWORDS:[/h] Italy; administrative database; diabetes mellitus; glycated hemoglobin; influenza vaccine

PMID: 32148720 PMCID: PMC6910755 DOI: 10.1136/fmch-2019-000198
 
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