tetano
Editor, Senior Moderator
Graefes Arch Clin Exp Ophthalmol
. 2020 Aug 29.
doi: 10.1007/s00417-020-04916-0. Online ahead of print.
Conjunctivitis in COVID-19 patients: frequency and clinical presentation
Noemi G?emes-Villahoz[SUP] 1 [/SUP], Barbara Burgos-Blasco[SUP] 2 [/SUP], Juli?n Garc?a-Feijo?[SUP] 3 [/SUP], Federico S?enz-Franc?s[SUP] 3 [/SUP], Pedro Arriola-Villalobos[SUP] 3 [/SUP], Jose Mar?a Martinez-de-la-Casa[SUP] 3 [/SUP], Jose Manuel Ben?tez-Del-Castillo[SUP] 3 [/SUP], Mar?a Herrera de la Muela[SUP] 4 [/SUP]
Affiliations
Abstract
Purpose: The purpose of this study was to evaluate the frequency and clinical presentation of conjunctivitis in hospitalized patients with COVID-19.
Methods: A cross-sectional study was conducted at the Hospital Clinico San Carlos of Madrid, Spain. A total of 301 subjects from the COVID admission unit with laboratory-confirmed SARS-CoV-2 infection were included. The presence and clinical characteristics of conjunctivitis were evaluated. Laboratory, radiological, and clinical results in patients with and without conjunctivitis stratified by sex were analyzed.
Results: Of the 301 subjects included, 180 patients (59.8%) were male and the median age was 72 years (IQ 59-82). Overall, 35 patients (11.6%) were diagnosed with acute conjunctivitis. We found no relationship between the COVID-19 severity score and the presence of conjunctivitis (P = 0.17). However, conjunctivitis was more frequent in males with moderate clinical severity and in women classified as clinically mild. The natural history of the disease seems to be a rapid self-limited conjunctivitis that improves without treatment and does not affect visual acuity nor associate short-term complications.
Conclusions: Approximately, 1 out of 10 hospitalized non-critical COVID-19 patients presents conjunctivitis during the disease. Compared with other viral conjunctivitis, we found distinctive clinical findings that could guide defining and differentiating conjunctivitis in COVID-19 patients.
Trial registration number: 20/336_E_COVID.
Keywords: COVID-19; Conjunctivitis; Coronavirus; Ocular; SARS-CoV-2.
. 2020 Aug 29.
doi: 10.1007/s00417-020-04916-0. Online ahead of print.
Conjunctivitis in COVID-19 patients: frequency and clinical presentation
Noemi G?emes-Villahoz[SUP] 1 [/SUP], Barbara Burgos-Blasco[SUP] 2 [/SUP], Juli?n Garc?a-Feijo?[SUP] 3 [/SUP], Federico S?enz-Franc?s[SUP] 3 [/SUP], Pedro Arriola-Villalobos[SUP] 3 [/SUP], Jose Mar?a Martinez-de-la-Casa[SUP] 3 [/SUP], Jose Manuel Ben?tez-Del-Castillo[SUP] 3 [/SUP], Mar?a Herrera de la Muela[SUP] 4 [/SUP]
Affiliations
- PMID: 32860573
- DOI: 10.1007/s00417-020-04916-0
Abstract
Purpose: The purpose of this study was to evaluate the frequency and clinical presentation of conjunctivitis in hospitalized patients with COVID-19.
Methods: A cross-sectional study was conducted at the Hospital Clinico San Carlos of Madrid, Spain. A total of 301 subjects from the COVID admission unit with laboratory-confirmed SARS-CoV-2 infection were included. The presence and clinical characteristics of conjunctivitis were evaluated. Laboratory, radiological, and clinical results in patients with and without conjunctivitis stratified by sex were analyzed.
Results: Of the 301 subjects included, 180 patients (59.8%) were male and the median age was 72 years (IQ 59-82). Overall, 35 patients (11.6%) were diagnosed with acute conjunctivitis. We found no relationship between the COVID-19 severity score and the presence of conjunctivitis (P = 0.17). However, conjunctivitis was more frequent in males with moderate clinical severity and in women classified as clinically mild. The natural history of the disease seems to be a rapid self-limited conjunctivitis that improves without treatment and does not affect visual acuity nor associate short-term complications.
Conclusions: Approximately, 1 out of 10 hospitalized non-critical COVID-19 patients presents conjunctivitis during the disease. Compared with other viral conjunctivitis, we found distinctive clinical findings that could guide defining and differentiating conjunctivitis in COVID-19 patients.
Trial registration number: 20/336_E_COVID.
Keywords: COVID-19; Conjunctivitis; Coronavirus; Ocular; SARS-CoV-2.