H9N2 avian influenza virus-derived natural reassortant H5N2 virus in swan containing the hemagglutinin segment from Eurasian H5 avian influenza virus

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Infect Genet Evol. 2016 Feb 21. pii: S1567-1348(16)30053-3. doi: 10.1016/j.meegid.2016.02.022. [Epub ahead of print]
[h=1]H9N2 avian influenza virus-derived natural reassortant H5N2 virus in swan containing the hemagglutinin segment from Eurasian H5 avian influenza virus with an in-frame deletion of four basic residues in the polybasic hemagglutinin cleavage site.[/h] Wang Y[SUP]1[/SUP], Yuan X[SUP]1[/SUP], Qi L[SUP]1[/SUP], Zhang Y[SUP]1[/SUP], Xu H[SUP]1[/SUP], Yang J[SUP]1[/SUP], Ai W[SUP]1[/SUP], Qi W[SUP]2[/SUP], Liao M[SUP]2[/SUP], Wang D[SUP]3[/SUP], Song M[SUP]4[/SUP], Li F[SUP]5[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] We isolated a novel H5N2 avian influenza virus from swans in China. The virus was derived from a widespread H9N2 avian influenza virus but acquired the hemagglutinin gene from Eurasian H5 subtype with a naturally occurring in-frame deletion of four basic residues in the polybasic hemagglutinin cleavage site.
Copyright ? 2015. Published by Elsevier B.V.


[h=4]KEYWORDS:[/h] Avian influenza virus; H5N2 subtype; H9N2 subtype; Hemagglutinin gene; Polybasic hemagglutinin cleavage site; Swan

PMID: 26910357 [PubMed - as supplied by publisher]