tetano
Editor, Senior Moderator
Immun Ageing. 2018 Nov 12;15:28. doi: 10.1186/s12979-018-0137-4. eCollection 2018.
[h=1]Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine.[/h] Camous X[SUP]1[/SUP], Visan L[SUP]2[/SUP], Ying CTT[SUP]1[/SUP], Abel B[SUP]3[/SUP], Nyunt MSZ[SUP]4[/SUP], Narang V[SUP]3[/SUP], Poidinger M[SUP]3[/SUP], Carre C[SUP]2[/SUP], Sesay S[SUP]5[/SUP], Bosco N[SUP]6[/SUP], Burdin N[SUP]2[/SUP], Tambyah PA[SUP]7[/SUP], Pin NT[SUP]4[/SUP], Larbi A[SUP]1,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]Abstract:[/h] Improving influenza vaccine efficacy is a priority to reduce the burden of influenza-associated morbidity and mortality. By careful selection of individuals based on health we show sustained response to influenza vaccination in older adults. Sustaining health in aging could be an important player in maintaining immune responses to influenza vaccination.
[h=4]Trial registration:[/h] NCT03266237. Registered 30 August 2017, https://clinicaltrials.gov/ct2/show/NCT03266237.
[h=4]KEYWORDS:[/h] Aging; Co-morbidity; Influenza vaccination; Stratification
PMID: 30455722 PMCID: PMC6231250 DOI: 10.1186/s12979-018-0137-4
Free PMC Article
[h=1]Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine.[/h] Camous X[SUP]1[/SUP], Visan L[SUP]2[/SUP], Ying CTT[SUP]1[/SUP], Abel B[SUP]3[/SUP], Nyunt MSZ[SUP]4[/SUP], Narang V[SUP]3[/SUP], Poidinger M[SUP]3[/SUP], Carre C[SUP]2[/SUP], Sesay S[SUP]5[/SUP], Bosco N[SUP]6[/SUP], Burdin N[SUP]2[/SUP], Tambyah PA[SUP]7[/SUP], Pin NT[SUP]4[/SUP], Larbi A[SUP]1,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]Abstract:[/h] Improving influenza vaccine efficacy is a priority to reduce the burden of influenza-associated morbidity and mortality. By careful selection of individuals based on health we show sustained response to influenza vaccination in older adults. Sustaining health in aging could be an important player in maintaining immune responses to influenza vaccination.
[h=4]Trial registration:[/h] NCT03266237. Registered 30 August 2017, https://clinicaltrials.gov/ct2/show/NCT03266237.
[h=4]KEYWORDS:[/h] Aging; Co-morbidity; Influenza vaccination; Stratification
PMID: 30455722 PMCID: PMC6231250 DOI: 10.1186/s12979-018-0137-4
Free PMC Article