tetano
Editor, Senior Moderator
Clinical Infectious Diseases
HIV-Infected Hospitalized Patients with 2009 Pandemic Influenza A (pH1N1)?United States, Spring and Summer 2009
1. Philip J. Peters1,
2. Jacek Skarbinski1,
3. Janice K. Louie2,
4. Seema Jain1,
5. New York City Department of Health Swine Flu Investigation Team3,
6. Michelle Roland4,
7. Shilpa G. Jani2,
8. Lyn Finelli1, and
9. John T. Brooks1
+ Author Affiliations
1.
1Centers for Disease Control and Prevention, Atlanta, Georgia
2.
2California Department of Public Health, Richmond, California
3.
3New York City Department of Health and Mental Hygiene, New York
4.
4California Department of Public Health, Sacramento, California
1. Correspondence: Dr Philip James Peters, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop E-45, Atlanta, GA 30333; or (pjpeters@cdc.gov).
Abstract
We describe the clinical findings of HIV-infected patients hospitalized with 2009 pandemic influenza A (pH1N1). Data were derived from 3 separate case series in the United States. Among 911 adults hospitalized with pH1N1 influenza, 31 (3.4%) were HIV infected compared with an HIV prevalence of 0.45% in the general US adult population. HIV-infected influenza patients experienced similar rates of intensive care unit admission (29% vs 34%) and death (13% vs 13%) compared with non?HIV-infected patients. Among HIV-infected patients with available data, 14 (50%) of 28 patients had a CD4 cell count <200 cells/μL, which was not associated with an increased risk of an intensive care unit admission or death. Overall, 25 (81%) HIV-infected patients received influenza antiviral therapy, but treatment was initiated within 48 h of illness onset in only 33% of cases. Clinicians should consider early empiric influenza antiviral treatment in HIV-infected patients presenting with suspected influenza.
http://cid.oxfordjournals.org/content/52/suppl_1/S183.full
HIV-Infected Hospitalized Patients with 2009 Pandemic Influenza A (pH1N1)?United States, Spring and Summer 2009
1. Philip J. Peters1,
2. Jacek Skarbinski1,
3. Janice K. Louie2,
4. Seema Jain1,
5. New York City Department of Health Swine Flu Investigation Team3,
6. Michelle Roland4,
7. Shilpa G. Jani2,
8. Lyn Finelli1, and
9. John T. Brooks1
+ Author Affiliations
1.
1Centers for Disease Control and Prevention, Atlanta, Georgia
2.
2California Department of Public Health, Richmond, California
3.
3New York City Department of Health and Mental Hygiene, New York
4.
4California Department of Public Health, Sacramento, California
1. Correspondence: Dr Philip James Peters, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop E-45, Atlanta, GA 30333; or (pjpeters@cdc.gov).
Abstract
We describe the clinical findings of HIV-infected patients hospitalized with 2009 pandemic influenza A (pH1N1). Data were derived from 3 separate case series in the United States. Among 911 adults hospitalized with pH1N1 influenza, 31 (3.4%) were HIV infected compared with an HIV prevalence of 0.45% in the general US adult population. HIV-infected influenza patients experienced similar rates of intensive care unit admission (29% vs 34%) and death (13% vs 13%) compared with non?HIV-infected patients. Among HIV-infected patients with available data, 14 (50%) of 28 patients had a CD4 cell count <200 cells/μL, which was not associated with an increased risk of an intensive care unit admission or death. Overall, 25 (81%) HIV-infected patients received influenza antiviral therapy, but treatment was initiated within 48 h of illness onset in only 33% of cases. Clinicians should consider early empiric influenza antiviral treatment in HIV-infected patients presenting with suspected influenza.
http://cid.oxfordjournals.org/content/52/suppl_1/S183.full