tetano
Editor, Senior Moderator
Hum Vaccin Immunother
. 2020 Sep 3;1-10.
doi: 10.1080/21645515.2020.1794684. Online ahead of print.
Current perspective on diagnosis, epidemiological assessment, prevention strategies, and potential therapeutic interventions for severe acute respiratory infections caused by 2019 novel coronavirus (SARS-CoV-2)
Komal Rizwan[SUP] 1 [/SUP], Tahir Rasheed[SUP] 2 [/SUP], Shakeel Ahmad Khan[SUP] 3 [/SUP], Muhammad Bilal[SUP] 4 [/SUP], Tahir Mahmood[SUP] 5 [/SUP]
Affiliations
Abstract
Coronaviruses are single-stranded RNA viruses that cause severe respiratory, enteric, and systemic infections in a vast range of hosts, including man, fish, mammals, and avian. Scientific interest has heightened on coronaviruses after the emergence of the 2019 novel Coronavirus (SARS-CoV-2). This review provides current perspectives on morphology, genetic diversity, transmission characteristics, replication cycle, diagnostic approaches, epidemiological assessment, and prevention strategies against the SARS-CoV-2. Moreover, different potential biotherapeutics such as small drug molecules, different vaccines, and immunotherapies to control severe acute respiratory infections caused by 2019 novel coronavirus (SARS-CoV-2) are repurposed and discussed with different mechanistic approaches. The current growth trends of the SARS-CoV-2/COVID-19 outbreak globally and preventive measures are briefly discussed. Furthermore, the lessons learned from the COVID-19 outbreak, so far, concluding remarks and future directions for controlling for COVID-19, are also recommended for a safer tomorrow.
Keywords: COVID-19; Coronavirus; diagnosis; epidemiology; prevention strategies; therapeutic candidates; transmission characteristics.
. 2020 Sep 3;1-10.
doi: 10.1080/21645515.2020.1794684. Online ahead of print.
Current perspective on diagnosis, epidemiological assessment, prevention strategies, and potential therapeutic interventions for severe acute respiratory infections caused by 2019 novel coronavirus (SARS-CoV-2)
Komal Rizwan[SUP] 1 [/SUP], Tahir Rasheed[SUP] 2 [/SUP], Shakeel Ahmad Khan[SUP] 3 [/SUP], Muhammad Bilal[SUP] 4 [/SUP], Tahir Mahmood[SUP] 5 [/SUP]
Affiliations
- PMID: 32881628
- DOI: 10.1080/21645515.2020.1794684
Abstract
Coronaviruses are single-stranded RNA viruses that cause severe respiratory, enteric, and systemic infections in a vast range of hosts, including man, fish, mammals, and avian. Scientific interest has heightened on coronaviruses after the emergence of the 2019 novel Coronavirus (SARS-CoV-2). This review provides current perspectives on morphology, genetic diversity, transmission characteristics, replication cycle, diagnostic approaches, epidemiological assessment, and prevention strategies against the SARS-CoV-2. Moreover, different potential biotherapeutics such as small drug molecules, different vaccines, and immunotherapies to control severe acute respiratory infections caused by 2019 novel coronavirus (SARS-CoV-2) are repurposed and discussed with different mechanistic approaches. The current growth trends of the SARS-CoV-2/COVID-19 outbreak globally and preventive measures are briefly discussed. Furthermore, the lessons learned from the COVID-19 outbreak, so far, concluding remarks and future directions for controlling for COVID-19, are also recommended for a safer tomorrow.
Keywords: COVID-19; Coronavirus; diagnosis; epidemiology; prevention strategies; therapeutic candidates; transmission characteristics.