tetano
Editor, Senior Moderator
Emerg Microbes Infect. 2019;8(1):1535-1545. doi: 10.1080/22221751.2019.1679611. [h=1]Human infection with a novel reassortant Eurasian-avian lineage swine H1N1 virus in northern China.[/h]
Li X[SUP]1[/SUP], Guo L[SUP]1[/SUP], Liu C[SUP]2[/SUP], Cheng Y[SUP]3[/SUP], Kong M[SUP]1[/SUP], Yang L[SUP]3[/SUP], Zhuang Z[SUP]1[/SUP], Liu J[SUP]3[/SUP], Zou M[SUP]1[/SUP], Dong X[SUP]1[/SUP], Su X[SUP]1[/SUP], Gu Q[SUP]1[/SUP].
[h=3]Author information[/h] 1 Tianjin Centers for Disease Control and Prevention, Tianjin, People's Republic of China. 2 Jizhou District Center for Disease Control and Prevention, Tianjin, People's Republic of China. 3 Chinese National Influenza Center, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.
[h=3]Abstract[/h] Influenza A virus infections occur in different species, causing mild to severe respiratory symptoms that lead to a heavy disease burden. Eurasian avian-like swine influenza A(H1N1) viruses (EAS-H1N1) are predominant in pigs and occasionally infect humans. An influenza A(H1N1) virus was isolated from a boy who was suffering from fever and headache and designated as A/Tianjin-baodi/1606/2018(H1N1). Full-genome sequencing and phylogenetic analysis revealed that A/Tianjin-baodi/1606/2018(H1N1) is a novel reassortant EAS-H1N1 containing gene segments from EAS-H1N1 (HA and NA), classical swine H1N1(NS) and A(H1N1)pdm09(PB2, PB2, PA, NP and M) viruses. The isolation and analysis of A/Tianjin-baodi/1606/2018(H1) provide further evidence that EAS-H1N1 poses a threat to human health and greater attention should be paid to surveillance of influenza virus infection in pigs and humans.
[h=4]KEYWORDS:[/h] EAS-H1N1; Influenza A virus; Phylogenetic analysis; molecular characteristics; triple-reassortant
PMID: 31661383 DOI: 10.1080/22221751.2019.1679611
Li X[SUP]1[/SUP], Guo L[SUP]1[/SUP], Liu C[SUP]2[/SUP], Cheng Y[SUP]3[/SUP], Kong M[SUP]1[/SUP], Yang L[SUP]3[/SUP], Zhuang Z[SUP]1[/SUP], Liu J[SUP]3[/SUP], Zou M[SUP]1[/SUP], Dong X[SUP]1[/SUP], Su X[SUP]1[/SUP], Gu Q[SUP]1[/SUP].
[h=3]Author information[/h] 1 Tianjin Centers for Disease Control and Prevention, Tianjin, People's Republic of China. 2 Jizhou District Center for Disease Control and Prevention, Tianjin, People's Republic of China. 3 Chinese National Influenza Center, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.
[h=3]Abstract[/h] Influenza A virus infections occur in different species, causing mild to severe respiratory symptoms that lead to a heavy disease burden. Eurasian avian-like swine influenza A(H1N1) viruses (EAS-H1N1) are predominant in pigs and occasionally infect humans. An influenza A(H1N1) virus was isolated from a boy who was suffering from fever and headache and designated as A/Tianjin-baodi/1606/2018(H1N1). Full-genome sequencing and phylogenetic analysis revealed that A/Tianjin-baodi/1606/2018(H1N1) is a novel reassortant EAS-H1N1 containing gene segments from EAS-H1N1 (HA and NA), classical swine H1N1(NS) and A(H1N1)pdm09(PB2, PB2, PA, NP and M) viruses. The isolation and analysis of A/Tianjin-baodi/1606/2018(H1) provide further evidence that EAS-H1N1 poses a threat to human health and greater attention should be paid to surveillance of influenza virus infection in pigs and humans.
[h=4]KEYWORDS:[/h] EAS-H1N1; Influenza A virus; Phylogenetic analysis; molecular characteristics; triple-reassortant
PMID: 31661383 DOI: 10.1080/22221751.2019.1679611