tetano
Editor, Senior Moderator
IDCases
. 2022;27:e01402.
doi: 10.1016/j.idcr.2022.e01402. Epub 2022 Jan 11.
Cytomegalovirus reactivation in critically-ill Coronavirus Disease 2019 patients: A case series of 11 patients
Myeongji Kim[SUP] 1 [/SUP], Jeffy Jacob[SUP] 1 [/SUP], Daniel Mayer[SUP] 2 [/SUP], Paula Andrea Eckardt[SUP] 3 [/SUP]
Affiliations
Abstract
The mortality associated with Coronavirus Disease 2019 is greatly influenced by known risk factors such as elderly age, cardiovascular disease, hypertension, diabetes, and immunosuppression. As cytomegalovirus reactivation in critically ill patients has been linked with higher morbidity and mortality in intensive care settings, it has been suggested that cytomegalovirus reactivation might lead to worse clinical outcomes of patients with Coronavirus Disease 2019. Here we describe the clinical course of 11 patients with Coronavirus Disease 2019 and concomitant cytomegalovirus viremia. We conclude that further research is necessary to formulate guidelines on diagnosis and treatment of cytomegalovirus reactivation in Coronavirus Disease 2019 patients.
Keywords: COVID-19; Coronavirus Disease-2019; Critical care; Cytomegalovirus; Cytomegalovirus reactivation; SARS-CoV-2.
. 2022;27:e01402.
doi: 10.1016/j.idcr.2022.e01402. Epub 2022 Jan 11.
Cytomegalovirus reactivation in critically-ill Coronavirus Disease 2019 patients: A case series of 11 patients
Myeongji Kim[SUP] 1 [/SUP], Jeffy Jacob[SUP] 1 [/SUP], Daniel Mayer[SUP] 2 [/SUP], Paula Andrea Eckardt[SUP] 3 [/SUP]
Affiliations
- PMID: 35036326
- PMCID: PMC8748205
- DOI: 10.1016/j.idcr.2022.e01402
Abstract
The mortality associated with Coronavirus Disease 2019 is greatly influenced by known risk factors such as elderly age, cardiovascular disease, hypertension, diabetes, and immunosuppression. As cytomegalovirus reactivation in critically ill patients has been linked with higher morbidity and mortality in intensive care settings, it has been suggested that cytomegalovirus reactivation might lead to worse clinical outcomes of patients with Coronavirus Disease 2019. Here we describe the clinical course of 11 patients with Coronavirus Disease 2019 and concomitant cytomegalovirus viremia. We conclude that further research is necessary to formulate guidelines on diagnosis and treatment of cytomegalovirus reactivation in Coronavirus Disease 2019 patients.
Keywords: COVID-19; Coronavirus Disease-2019; Critical care; Cytomegalovirus; Cytomegalovirus reactivation; SARS-CoV-2.