tetano
Editor, Senior Moderator
Hum Vaccin Immunother. 2018 May 31:1-8. doi: 10.1080/21645515.2018.1482172. [Epub ahead of print]
[h=1]Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine.[/h] Lee H[SUP]1[/SUP], Shim EH[SUP]1[/SUP], You S[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccination and recommend the inoculation of only strains lower than protective levels.
[h=4]KEYWORDS:[/h] Influenza; immunodominance hierarchy; vaccine effectiveness
PMID: 29852081 DOI: 10.1080/21645515.2018.1482172
[h=1]Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine.[/h] Lee H[SUP]1[/SUP], Shim EH[SUP]1[/SUP], You S[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccination and recommend the inoculation of only strains lower than protective levels.
[h=4]KEYWORDS:[/h] Influenza; immunodominance hierarchy; vaccine effectiveness
PMID: 29852081 DOI: 10.1080/21645515.2018.1482172