tetano
Editor, Senior Moderator
Tuberc Respir Dis (Seoul). 2017 Sep 1. doi: 10.4046/trd.2016.0015. [Epub ahead of print]
[h=1]Incidence and Risk Factors of Pneumonia in Hospitalized Patients with Seasonal Influenza A or B.[/h] Chu S[SUP]#[/SUP][SUP]1[/SUP], Park SJ[SUP]#[/SUP][SUP]1[/SUP], Koo SM[SUP]1[/SUP], Kim YK[SUP]1[/SUP], Kim KU[SUP]1[/SUP], Uh ST[SUP]2[/SUP], Kim TH[SUP]3[/SUP], Park S[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Most patients with influenza recover spontaneously or following treatment with an anti-viral agent, but some patients experience pneumonia requiring hospitalization. We conducted a retrospective review to determine the incidence and risk factors of pneumonia in hospitalized patients with influenza A or B.
[h=4]METHODS:[/h] A total of 213 patients aged 18 years or older and hospitalized with influenza between January 2012 and January 2015 were included in this study. A reverse-transcriptase polymerase chain reaction assay was used to detect the influenza A or B virus in the patients' sputum samples. We collected demographic and laboratory data, combined coexisting diseases, and radiologic findings.
[h=4]RESULTS:[/h] The incidence of pneumonia was higher in patients in the influenza A group compared to those in the influenza B group (68.6% vs. 56.9%), but this difference was not statistically significant. The presence of underlying respiratory disease was significantly associated with pneumonia in the influenza A group (adjusted odds ratio [OR], 3.975; 95% confidence interval [CI], 1.312-12.043; p=0.015). In the influenza B group, the white blood cell count (adjusted OR, 1.413; 95% CI, 1.053-1.896; p=0.021), platelet count (adjusted OR, 0.988; 95% CI, 0.978-0.999; p=0.027), and existence of an underlying medical disease (adjusted OR, 15.858; 95% CI, 1.757-143.088; p=0.014) were all significantly associated with pneumonia in multivariate analyses.
[h=4]CONCLUSION:[/h] The incidence of pneumonia was 65.7% in hospitalized patients with influenza A or B. The risk factors of pneumonia differed in hospitalized patients with influenza A or B.
[h=4]KEYWORDS:[/h] Comorbidity; Influenza; Pneumonia; Risk Factors
PMID: 28905532 DOI: 10.4046/trd.2016.0015
[h=1]Incidence and Risk Factors of Pneumonia in Hospitalized Patients with Seasonal Influenza A or B.[/h] Chu S[SUP]#[/SUP][SUP]1[/SUP], Park SJ[SUP]#[/SUP][SUP]1[/SUP], Koo SM[SUP]1[/SUP], Kim YK[SUP]1[/SUP], Kim KU[SUP]1[/SUP], Uh ST[SUP]2[/SUP], Kim TH[SUP]3[/SUP], Park S[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Most patients with influenza recover spontaneously or following treatment with an anti-viral agent, but some patients experience pneumonia requiring hospitalization. We conducted a retrospective review to determine the incidence and risk factors of pneumonia in hospitalized patients with influenza A or B.
[h=4]METHODS:[/h] A total of 213 patients aged 18 years or older and hospitalized with influenza between January 2012 and January 2015 were included in this study. A reverse-transcriptase polymerase chain reaction assay was used to detect the influenza A or B virus in the patients' sputum samples. We collected demographic and laboratory data, combined coexisting diseases, and radiologic findings.
[h=4]RESULTS:[/h] The incidence of pneumonia was higher in patients in the influenza A group compared to those in the influenza B group (68.6% vs. 56.9%), but this difference was not statistically significant. The presence of underlying respiratory disease was significantly associated with pneumonia in the influenza A group (adjusted odds ratio [OR], 3.975; 95% confidence interval [CI], 1.312-12.043; p=0.015). In the influenza B group, the white blood cell count (adjusted OR, 1.413; 95% CI, 1.053-1.896; p=0.021), platelet count (adjusted OR, 0.988; 95% CI, 0.978-0.999; p=0.027), and existence of an underlying medical disease (adjusted OR, 15.858; 95% CI, 1.757-143.088; p=0.014) were all significantly associated with pneumonia in multivariate analyses.
[h=4]CONCLUSION:[/h] The incidence of pneumonia was 65.7% in hospitalized patients with influenza A or B. The risk factors of pneumonia differed in hospitalized patients with influenza A or B.
[h=4]KEYWORDS:[/h] Comorbidity; Influenza; Pneumonia; Risk Factors
PMID: 28905532 DOI: 10.4046/trd.2016.0015