tetano
Editor, Senior Moderator
Indian J Crit Care Med
. 2021 Oct;25(10):1193-1196.
doi: 10.5005/jp-journals-10071-23986.
Mucormycosis: A Case Series of Patients Admitted in Non-COVID-19 Intensive Care Unit of a Tertiary Care Center during the Second Wave
Sangam Yadav[SUP] 1 [/SUP], Ankur Sharma[SUP] 2 [/SUP], Nikhil Kothari[SUP] 1 [/SUP], Pradeep K Bhatia[SUP] 1 [/SUP], Shilpa Goyal[SUP] 1 [/SUP], Amit Goyal[SUP] 3 [/SUP]
Affiliations
Abstract
Rhino-orbital-cerebral mucormycosis is an invasive fungal infection associated with mortality of 25-62%. There has been a surge in the number of cases during this second wave of coronavirus disease-2019 (COVID-19) in India. We report 10 cases of mucormycosis admitted to our adult intensive care unit. After reviewing the patient's information, we found that 60% of patients had received steroids, and most had uncontrolled blood sugar levels. Most patients received treatment with surgical debridement and antifungal, although the mortality rate was as high as 40%. We report two unique cases of renal and gastrointestinal mucormycosis as well. We concluded that poor glycemic control was the primary etiology behind the rise in the number of cases. Our report also stresses the importance of early surgical intervention and suggests further research comparing the efficacy of combination antifungal therapy versus single antifungal (amphotericin B) to help resource-limited settings in these times of drug crisis. How to cite this article: Yadav S, Sharma A, Kothari N, Bhatia PK, Goyal S, Goyal A. Mucormycosis: A Case Series of Patients Admitted in Non-COVID-19 Intensive Care Unit of a Tertiary Care Center during the Second Wave. Indian J Crit Care Med 2021;25(10):1193-1196.
Keywords: COVID-19; Intensive care unit; Mucormycosis.
. 2021 Oct;25(10):1193-1196.
doi: 10.5005/jp-journals-10071-23986.
Mucormycosis: A Case Series of Patients Admitted in Non-COVID-19 Intensive Care Unit of a Tertiary Care Center during the Second Wave
Sangam Yadav[SUP] 1 [/SUP], Ankur Sharma[SUP] 2 [/SUP], Nikhil Kothari[SUP] 1 [/SUP], Pradeep K Bhatia[SUP] 1 [/SUP], Shilpa Goyal[SUP] 1 [/SUP], Amit Goyal[SUP] 3 [/SUP]
Affiliations
- PMID: 34916755
- PMCID: PMC8645818
- DOI: 10.5005/jp-journals-10071-23986
Abstract
Rhino-orbital-cerebral mucormycosis is an invasive fungal infection associated with mortality of 25-62%. There has been a surge in the number of cases during this second wave of coronavirus disease-2019 (COVID-19) in India. We report 10 cases of mucormycosis admitted to our adult intensive care unit. After reviewing the patient's information, we found that 60% of patients had received steroids, and most had uncontrolled blood sugar levels. Most patients received treatment with surgical debridement and antifungal, although the mortality rate was as high as 40%. We report two unique cases of renal and gastrointestinal mucormycosis as well. We concluded that poor glycemic control was the primary etiology behind the rise in the number of cases. Our report also stresses the importance of early surgical intervention and suggests further research comparing the efficacy of combination antifungal therapy versus single antifungal (amphotericin B) to help resource-limited settings in these times of drug crisis. How to cite this article: Yadav S, Sharma A, Kothari N, Bhatia PK, Goyal S, Goyal A. Mucormycosis: A Case Series of Patients Admitted in Non-COVID-19 Intensive Care Unit of a Tertiary Care Center during the Second Wave. Indian J Crit Care Med 2021;25(10):1193-1196.
Keywords: COVID-19; Intensive care unit; Mucormycosis.