tetano
Editor, Senior Moderator
Infect Dis Now
. 2023 Feb 10;104673.
doi: 10.1016/j.idnow.2023.104673. Online ahead of print.
Symptoms of Long-COVID 1-Year After a COVID-19 Outbreak Among Sailors on a French Aircraft Carrier
Anne Perisse[SUP] 1 [/SUP], François De Cacqueray[SUP] 2 [/SUP], David Delarbre[SUP] 3 [/SUP], Hélène Marsaa[SUP] 1 [/SUP], Cedric Bergmann[SUP] 4 [/SUP], Virginie Da Silva[SUP] 5 [/SUP], Antoine Bronstein[SUP] 6 [/SUP], Nicolas Paleiron[SUP] 6 [/SUP], Nastasia Menoud[SUP] 7 [/SUP], Jacques Cobola[SUP] 7 [/SUP], Catherine Verret[SUP] 8 [/SUP], Aurélie Mayet[SUP] 9 [/SUP], Olivier Bylicki[SUP] 10 [/SUP]
Affiliations
Abstract
Objectives: While persistent symptoms have been reported after the coronavirus disease-2019 (COVID-19), long-term data on outpatients with mild COVID-19 are lacking. The objective was to describe symptoms persisting for 12 months.
Methods: This prospective cohort study on 1767 sailors of an aircraft carrier in which a Covid-19 outbreak occurred during a mission in April 2020 described predefined self-reported symptoms of Long-COVID at 6, 9 and 12 months. Logistic-regression analyses were used to identify correlates for Long-COVID at months 6, 9 and 12.
Results: Among the 641 participants, 619 (35%) completed at least one follow-up questionnaire (413 COVID-positive and 206 COVID-negative). Symptoms of Long-COVID were reported by 53.7%, 55.2% and 54.3% of COVID-positive participants vs. 31.2%, 23.3% and 40.0% in COVID-negative patients, at 6 (p<.002), 9 (p<.002) and 12 months (p=.13), respectively. The most frequent symptoms reported were concentration and memory difficulties, asthenia and sleep disorders.
Conclusion: In this study more than half of COVID-positive outpatients reported persistent symptoms up to 12 months post-quarantine. These findings suggests that all patients, including those with mild disease, can be affected by Long-COVID. A lack of difference at 12 months with COVID-negative patienys prompts caution. The symptoms of Long-COVID are so non-specific that they may be viewed as the consequence of multiple intercurrent factors.
Keywords: Aircraft-carrier; SARS-CoV2; Symptoms of Long-COVID; long term symptoms.
. 2023 Feb 10;104673.
doi: 10.1016/j.idnow.2023.104673. Online ahead of print.
Symptoms of Long-COVID 1-Year After a COVID-19 Outbreak Among Sailors on a French Aircraft Carrier
Anne Perisse[SUP] 1 [/SUP], François De Cacqueray[SUP] 2 [/SUP], David Delarbre[SUP] 3 [/SUP], Hélène Marsaa[SUP] 1 [/SUP], Cedric Bergmann[SUP] 4 [/SUP], Virginie Da Silva[SUP] 5 [/SUP], Antoine Bronstein[SUP] 6 [/SUP], Nicolas Paleiron[SUP] 6 [/SUP], Nastasia Menoud[SUP] 7 [/SUP], Jacques Cobola[SUP] 7 [/SUP], Catherine Verret[SUP] 8 [/SUP], Aurélie Mayet[SUP] 9 [/SUP], Olivier Bylicki[SUP] 10 [/SUP]
Affiliations
- PMID: 36775065
- DOI: 10.1016/j.idnow.2023.104673
Abstract
Objectives: While persistent symptoms have been reported after the coronavirus disease-2019 (COVID-19), long-term data on outpatients with mild COVID-19 are lacking. The objective was to describe symptoms persisting for 12 months.
Methods: This prospective cohort study on 1767 sailors of an aircraft carrier in which a Covid-19 outbreak occurred during a mission in April 2020 described predefined self-reported symptoms of Long-COVID at 6, 9 and 12 months. Logistic-regression analyses were used to identify correlates for Long-COVID at months 6, 9 and 12.
Results: Among the 641 participants, 619 (35%) completed at least one follow-up questionnaire (413 COVID-positive and 206 COVID-negative). Symptoms of Long-COVID were reported by 53.7%, 55.2% and 54.3% of COVID-positive participants vs. 31.2%, 23.3% and 40.0% in COVID-negative patients, at 6 (p<.002), 9 (p<.002) and 12 months (p=.13), respectively. The most frequent symptoms reported were concentration and memory difficulties, asthenia and sleep disorders.
Conclusion: In this study more than half of COVID-positive outpatients reported persistent symptoms up to 12 months post-quarantine. These findings suggests that all patients, including those with mild disease, can be affected by Long-COVID. A lack of difference at 12 months with COVID-negative patienys prompts caution. The symptoms of Long-COVID are so non-specific that they may be viewed as the consequence of multiple intercurrent factors.
Keywords: Aircraft-carrier; SARS-CoV2; Symptoms of Long-COVID; long term symptoms.