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Infection . A fatal course of COVID-19 during the Omicron surge: can you estimate your patients' SARS-CoV-2 immune status?

tetano

Editor, Senior Moderator
Infection


. 2023 Nov 6.
doi: 10.1007/s15010-023-02120-w. Online ahead of print. A fatal course of COVID-19 during the Omicron surge: can you estimate your patients' SARS-CoV-2 immune status?

Martin Mersch[SUP] 1 [/SUP], Stefan Schlabe[SUP] 1 2 [/SUP], Sven Breitschwerdt[SUP] 1 2 [/SUP], Judith Laufenberg[SUP] 1 2 [/SUP], Dorian Emmert[SUP] 3 [/SUP], Souhaib Aldabbagh[SUP] 3 [/SUP], Christoph Boesecke[SUP] 1 2 [/SUP], Malte Benedikt Monin[SUP] 4 5 [/SUP]



Affiliations
Abstract

We present a case of an ultimately fatal course of COVID-19 (coronavirus disease-19) in an 81-year-old female patient during the Omicron surge. The patient did not represent the typical patient at risk for severe COVID-19 with significant causes of immunodeficiency. However, she had been skeptical about the vaccination for severe acute respiratory syndrome virus-2 (SARS-CoV-2) and had refused it. Moreover, there had been no previous COVID-19 episodes. Our case report illustrates that with regard to SARS-CoV-2, immunologically naive patients are still at risk for severe and/or even fatal courses of COVID-19. We call to implement both, recommendations for SARS-CoV-2 vaccinations as well as for antiviral treatment.

Keywords: COVID-19; Immune status; Omicron variant of concern; Severe course.

 
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