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Influenza and Other Respiratory Viruses: Influenza C virus?associated community-acquired pneumonia in children

tetano

Editor, Senior Moderator
Influenza C virus?associated community-acquired pneumonia in children

Nicola Principi,
Alessia Scala,
Cristina Daleno,
Susanna Esposito*

Article first published online: 7 DEC 2012

DOI: 10.1111/irv.12062



To evaluate the impact of influenza C (ICV) infection in children with community-acquired pneumonia (CAP), all of the children consecutively seen during 4 influenza seasons with respiratory symptoms and radiographically confirmed CAP were prospectively evaluated. ICV was identified in the respiratory secretions of five of 391 patients (1?3%). In children with ICV-associated CAP, clinical data were similar to those observed in children with IAV-associated CAP and worse than those observed in children with IBV-associated. The phylogenetic tree showed that the sequenced strains clustered in two of the six ICV lineages. These findings highlight that ICV can be a cause of CAP of children and that this can be severe enough to require hospitalization.


http://onlinelibrary.wiley.com/doi/10.1111/irv.12062/abstract
 
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