tetano
Editor, Senior Moderator
Pediatr Infect Dis J. 2015 Aug 28. [Epub ahead of print]
[h=1]Influenza and Pertussis Vaccination among Pregnant Women and their Infants' Close Contacts: Reported Practices and Attitudes.[/h] O'Leary S[SUP]1[/SUP], Pyrzanowski J, Brewer SE, Barnard J, Beaty B, Donnelly M, Mazzoni S, Dempsey AF.
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]OBJECTIVES:[/h] Our objectives were to describe, among post-partum women, receipt of influenza and tetanus-diphtheria-acellular-pertussis (Tdap) vaccines in themselves and close contacts, and factors associated with cocooning.
[h=4]METHODS:[/h] A survey February-April 2013 of 613 post-partum women from 9 obstetrics practices assessed vaccine receipt among respondents and close contacts, demographics, and fivedomains of health beliefs[benefits, barriers, susceptibility, severity, and social norms]. Multivariable models assessed the association of these factors with Tdap or influenza 'cocooning,' defined as the mother plus at least one close contact of her newborn receiving the vaccine.
[h=4]RESULTS:[/h] The response rate was 45%; 61% of mothers reported they and at least one close contact of their newborn had received influenza vaccine, and 67% reported this for Tdap. Infants whose mothers received influenza vaccine had a mean of 2.8 close contacts who also received influenza vaccine versus 0.9 contacts for mothers who did not receive influenza vaccine (p<0.0001).Infants whose mothers received Tdap had on average 2.4 contacts who also received it versus 0.8 for mothers who did not receive Tdap (p<0.0001). Factors associated with influenza and Tdap cocooning included obstetrician recommendation, high perceived benefits, low perceived barriers, and perceived susceptibility to disease. For Tdap, race/ethnicity was associated with cocooning (Hispanic/Latino, adjusted odds ratio 0.26, 95% confidence interval 0.10-0.64 referent to White).
[h=4]CONCLUSION:[/h] Maternal vaccination and obstetrician recommendation are associated with infant cocooning. Interventions to increase cocooning of infants should focus on encouraging strong provider recommendations, increasing maternal knowledge of disease risk, and addressing identified barriers. Reasons for possible racial/ethnic differences should be further explored.
PMID: 26322660 [PubMed - as supplied by publisher]
[h=1]Influenza and Pertussis Vaccination among Pregnant Women and their Infants' Close Contacts: Reported Practices and Attitudes.[/h] O'Leary S[SUP]1[/SUP], Pyrzanowski J, Brewer SE, Barnard J, Beaty B, Donnelly M, Mazzoni S, Dempsey AF.
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]OBJECTIVES:[/h] Our objectives were to describe, among post-partum women, receipt of influenza and tetanus-diphtheria-acellular-pertussis (Tdap) vaccines in themselves and close contacts, and factors associated with cocooning.
[h=4]METHODS:[/h] A survey February-April 2013 of 613 post-partum women from 9 obstetrics practices assessed vaccine receipt among respondents and close contacts, demographics, and fivedomains of health beliefs[benefits, barriers, susceptibility, severity, and social norms]. Multivariable models assessed the association of these factors with Tdap or influenza 'cocooning,' defined as the mother plus at least one close contact of her newborn receiving the vaccine.
[h=4]RESULTS:[/h] The response rate was 45%; 61% of mothers reported they and at least one close contact of their newborn had received influenza vaccine, and 67% reported this for Tdap. Infants whose mothers received influenza vaccine had a mean of 2.8 close contacts who also received influenza vaccine versus 0.9 contacts for mothers who did not receive influenza vaccine (p<0.0001).Infants whose mothers received Tdap had on average 2.4 contacts who also received it versus 0.8 for mothers who did not receive Tdap (p<0.0001). Factors associated with influenza and Tdap cocooning included obstetrician recommendation, high perceived benefits, low perceived barriers, and perceived susceptibility to disease. For Tdap, race/ethnicity was associated with cocooning (Hispanic/Latino, adjusted odds ratio 0.26, 95% confidence interval 0.10-0.64 referent to White).
[h=4]CONCLUSION:[/h] Maternal vaccination and obstetrician recommendation are associated with infant cocooning. Interventions to increase cocooning of infants should focus on encouraging strong provider recommendations, increasing maternal knowledge of disease risk, and addressing identified barriers. Reasons for possible racial/ethnic differences should be further explored.
PMID: 26322660 [PubMed - as supplied by publisher]