tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2016 Jul 4. doi: 10.1111/irv.12402. [Epub ahead of print]
[h=1]Influenza C infections in Western Australia and Victoria from 2008-14.[/h] Jelley L[SUP]1[/SUP], Levy A[SUP]2,[/SUP][SUP]3[/SUP], Deng YM[SUP]1[/SUP], Spirason N[SUP]1[/SUP], Lang J[SUP]2[/SUP], Buettner I[SUP]1[/SUP], Druce J[SUP]4[/SUP], Blyth C[SUP]5,[/SUP][SUP]6,[/SUP][SUP]7[/SUP], Effler P[SUP]3,[/SUP][SUP]5,[/SUP][SUP]8[/SUP], Smith D[SUP]2,[/SUP][SUP]8[/SUP], Barr IG[SUP]1,[/SUP][SUP]9[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Influenza C is usually considered a minor cause of respiratory illness in man with many infections being asymptomatic or clinically mild. Large outbreaks can occur periodically resulting in significant morbidity.
[h=4]OBJECTIVES:[/h] This study was aimed at analyzing the available influenza C clinical samples from two widely separated states of Australia, collected over a seven year period and to compare them with influenza C viruses detected in other parts of the world in recent years.
[h=4]PATIENTS/METHODS:[/h] Between 2008 and 2014, 86 respiratory samples that were influenza C positive were collected from subjects with influenza like illness living in the states of Victoria and Western Australia. A battery of other respiratory viruses were also tested for in these influenza C positive samples. Virus isolation was attempted on all of these clinical samples and gene sequencing was performed on all influenza C positive cultures.
[h=4]RESULTS AND CONCLUSIONS:[/h] Detections of influenza C in respiratory samples were sporadic in most years studied, but higher rates of infection occurred in 2012 and 2014. Many of the patients with influenza C had co-infections with other respiratory pathogens. Phylogenetic analysis of the full length haemagglutinin-esterase fusion (HE) gene found that most of the viruses grouped in the C/Sao Paulo/378/82 clade with the remainder grouping in the C/Kanagawa/1/76 clade. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Australia; children; influenza C; respiratory disease; viruses
PMID: 27373693 DOI: 10.1111/irv.12402
[PubMed - as supplied by publisher]
[h=1]Influenza C infections in Western Australia and Victoria from 2008-14.[/h] Jelley L[SUP]1[/SUP], Levy A[SUP]2,[/SUP][SUP]3[/SUP], Deng YM[SUP]1[/SUP], Spirason N[SUP]1[/SUP], Lang J[SUP]2[/SUP], Buettner I[SUP]1[/SUP], Druce J[SUP]4[/SUP], Blyth C[SUP]5,[/SUP][SUP]6,[/SUP][SUP]7[/SUP], Effler P[SUP]3,[/SUP][SUP]5,[/SUP][SUP]8[/SUP], Smith D[SUP]2,[/SUP][SUP]8[/SUP], Barr IG[SUP]1,[/SUP][SUP]9[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Influenza C is usually considered a minor cause of respiratory illness in man with many infections being asymptomatic or clinically mild. Large outbreaks can occur periodically resulting in significant morbidity.
[h=4]OBJECTIVES:[/h] This study was aimed at analyzing the available influenza C clinical samples from two widely separated states of Australia, collected over a seven year period and to compare them with influenza C viruses detected in other parts of the world in recent years.
[h=4]PATIENTS/METHODS:[/h] Between 2008 and 2014, 86 respiratory samples that were influenza C positive were collected from subjects with influenza like illness living in the states of Victoria and Western Australia. A battery of other respiratory viruses were also tested for in these influenza C positive samples. Virus isolation was attempted on all of these clinical samples and gene sequencing was performed on all influenza C positive cultures.
[h=4]RESULTS AND CONCLUSIONS:[/h] Detections of influenza C in respiratory samples were sporadic in most years studied, but higher rates of infection occurred in 2012 and 2014. Many of the patients with influenza C had co-infections with other respiratory pathogens. Phylogenetic analysis of the full length haemagglutinin-esterase fusion (HE) gene found that most of the viruses grouped in the C/Sao Paulo/378/82 clade with the remainder grouping in the C/Kanagawa/1/76 clade. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Australia; children; influenza C; respiratory disease; viruses
PMID: 27373693 DOI: 10.1111/irv.12402
[PubMed - as supplied by publisher]