tetano
Editor, Senior Moderator
Influenza Other Respir Viruses
. 2023 Oct 15;17(10):e13208.
doi: 10.1111/irv.13208. eCollection 2023 Oct. Characterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022
Yuan Liang[SUP] 1 [/SUP], Charlotte K Hjulsager[SUP] 2 [/SUP], Tim K Jensen[SUP] 1 [/SUP], Anne Sofie V Hammer[SUP] 1 [/SUP], Maibritt T Ovesen[SUP] 1 [/SUP], Lars E Larsen[SUP] 1 [/SUP]
Affiliations
In 2021 and 2022, clade 2.3.4.4b H5Nx high pathogenicity avian influenza viruses were detected in one harbor seal and in one adult and three fox cubs in Denmark. The viruses were closely related to contemporary viruses found in Europe, and some had obtained amino acid substitutions related to mammalian adaptation. Notably, the virus distribution appeared to have been different in the infected fox cubs, as one exclusively tested positive for the presence of HPAIV in the brain and the other two only in the lung. Collectively, these findings stress the need for increased disease surveillance of wild and farmed mammals.
Keywords: Denmark; high pathogenicity avian influenza; influenza A virus; mammals; wild birds.
. 2023 Oct 15;17(10):e13208.
doi: 10.1111/irv.13208. eCollection 2023 Oct. Characterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022
Yuan Liang[SUP] 1 [/SUP], Charlotte K Hjulsager[SUP] 2 [/SUP], Tim K Jensen[SUP] 1 [/SUP], Anne Sofie V Hammer[SUP] 1 [/SUP], Maibritt T Ovesen[SUP] 1 [/SUP], Lars E Larsen[SUP] 1 [/SUP]
Affiliations
- PMID: 37850154
- PMCID: PMC10577164
- DOI: 10.1111/irv.13208
In 2021 and 2022, clade 2.3.4.4b H5Nx high pathogenicity avian influenza viruses were detected in one harbor seal and in one adult and three fox cubs in Denmark. The viruses were closely related to contemporary viruses found in Europe, and some had obtained amino acid substitutions related to mammalian adaptation. Notably, the virus distribution appeared to have been different in the infected fox cubs, as one exclusively tested positive for the presence of HPAIV in the brain and the other two only in the lung. Collectively, these findings stress the need for increased disease surveillance of wild and farmed mammals.
Keywords: Denmark; high pathogenicity avian influenza; influenza A virus; mammals; wild birds.