tetano
Editor, Senior Moderator
Influenza Other Respir Viruses
. 2024 Jul;18(7):e13352.
doi: 10.1111/irv.13352. Incidence of Hospitalization due to Influenza-Associated Severe Acute Respiratory Infection During 2010-2019 in Bangladesh
Mohammad Abdul Aleem[SUP] 1 [/SUP], Katherine Roguski DeBord[SUP] 2 [/SUP], Makhdum Ahmed[SUP] 3 [/SUP], Mohammed Ziaur Rahman[SUP] 4 [/SUP], Mustafizur Rahman[SUP] 5 [/SUP], Md Ariful Islam[SUP] 1 [/SUP], A S M Alamgir[SUP] 6 [/SUP], M Salimuzzaman[SUP] 6 [/SUP], Tahmina Shirin[SUP] 6 [/SUP], Mohammod Jobayer Chisti[SUP] 7 [/SUP], Mahmudur Rahman[SUP] 8 [/SUP], Eduardo Azziz-Baumgartner[SUP] 9 [/SUP], Fahmida Chowdhury[SUP] 1 [/SUP], A Danielle Iuliano[SUP] 10 [/SUP]
Affiliations
Background: Global influenza-associated acute respiratory infections contribute to 3-5 million severe illnesses requiring hospitalization annually, with 90% of hospitalizations occurring among children < 5 years in developing countries. In Bangladesh, the inadequate availability of nationally representative, robust estimates of influenza-associated hospitalizations limits allocation of resources for prevention and control measures.
Methods: This study used data from the hospital-based influenza surveillance (HBIS) system in Bangladesh from 2010 to 2019 and healthcare utilization surveys to determine hospital utilization patterns in the catchment area. We estimated annual influenza-associated hospitalization numbers and rates for all age groups in Bangladesh using WHO methods, adjusted for a 6-day-a-week enrollment schedule, selective testing of specimens from children under five, and healthcare-seeking behavior, based on the proportion of symptomatic community participants seeking healthcare within the past week. We then estimated national hospitalization rates by multiplying age-specific hospitalization rates with the corresponding annual national census population.
Results: Annual influenza-associated hospitalization rates per 100,000 population for all ages ranged from 31 (95% CI: 27-36) in 2011 to 139 (95% CI: 130-149) in 2019. Children < 5 years old had the highest rates of influenza-associated hospitalization, ranging from 114 (95% CI: 90-138) in 2011 to 529 (95% CI: 481-578) in 2019, followed by adults aged ≥ 65 years with rates ranging from 46 (95% CI: 34-57) in 2012 to 252 (95% CI: 213-292) in 2019. The national hospitalization estimates for all ages during 2010-2019 ranged from 47,891 to 236,380 per year.
Conclusions: The impact of influenza-associated hospitalizations in Bangladesh may be considerable, particularly for young children and older adults. Targeted interventions, such as influenza vaccination for these age groups, should be prioritized and evaluated.
Keywords: Bangladesh; acute respiratory illness; hospitalization; influenza; respiratory infections; seasonal; surveillance.
. 2024 Jul;18(7):e13352.
doi: 10.1111/irv.13352. Incidence of Hospitalization due to Influenza-Associated Severe Acute Respiratory Infection During 2010-2019 in Bangladesh
Mohammad Abdul Aleem[SUP] 1 [/SUP], Katherine Roguski DeBord[SUP] 2 [/SUP], Makhdum Ahmed[SUP] 3 [/SUP], Mohammed Ziaur Rahman[SUP] 4 [/SUP], Mustafizur Rahman[SUP] 5 [/SUP], Md Ariful Islam[SUP] 1 [/SUP], A S M Alamgir[SUP] 6 [/SUP], M Salimuzzaman[SUP] 6 [/SUP], Tahmina Shirin[SUP] 6 [/SUP], Mohammod Jobayer Chisti[SUP] 7 [/SUP], Mahmudur Rahman[SUP] 8 [/SUP], Eduardo Azziz-Baumgartner[SUP] 9 [/SUP], Fahmida Chowdhury[SUP] 1 [/SUP], A Danielle Iuliano[SUP] 10 [/SUP]
Affiliations
- PMID: 39005150
- PMCID: PMC11247272
- DOI: 10.1111/irv.13352
Background: Global influenza-associated acute respiratory infections contribute to 3-5 million severe illnesses requiring hospitalization annually, with 90% of hospitalizations occurring among children < 5 years in developing countries. In Bangladesh, the inadequate availability of nationally representative, robust estimates of influenza-associated hospitalizations limits allocation of resources for prevention and control measures.
Methods: This study used data from the hospital-based influenza surveillance (HBIS) system in Bangladesh from 2010 to 2019 and healthcare utilization surveys to determine hospital utilization patterns in the catchment area. We estimated annual influenza-associated hospitalization numbers and rates for all age groups in Bangladesh using WHO methods, adjusted for a 6-day-a-week enrollment schedule, selective testing of specimens from children under five, and healthcare-seeking behavior, based on the proportion of symptomatic community participants seeking healthcare within the past week. We then estimated national hospitalization rates by multiplying age-specific hospitalization rates with the corresponding annual national census population.
Results: Annual influenza-associated hospitalization rates per 100,000 population for all ages ranged from 31 (95% CI: 27-36) in 2011 to 139 (95% CI: 130-149) in 2019. Children < 5 years old had the highest rates of influenza-associated hospitalization, ranging from 114 (95% CI: 90-138) in 2011 to 529 (95% CI: 481-578) in 2019, followed by adults aged ≥ 65 years with rates ranging from 46 (95% CI: 34-57) in 2012 to 252 (95% CI: 213-292) in 2019. The national hospitalization estimates for all ages during 2010-2019 ranged from 47,891 to 236,380 per year.
Conclusions: The impact of influenza-associated hospitalizations in Bangladesh may be considerable, particularly for young children and older adults. Targeted interventions, such as influenza vaccination for these age groups, should be prioritized and evaluated.
Keywords: Bangladesh; acute respiratory illness; hospitalization; influenza; respiratory infections; seasonal; surveillance.