tetano
Editor, Senior Moderator
Influenza Other Respir Viruses
. 2022 Jun 30.
doi: 10.1111/irv.13003. Online ahead of print.
Modelled estimates of hospitalisations attributable to respiratory syncytial virus and influenza in Australia, 2009-2017
Allen L Nazareno[SUP] 1 2 [/SUP], David J Muscatello[SUP] 1 [/SUP], Robin M Turner[SUP] 3 [/SUP], James G Wood[SUP] 1 [/SUP], Hannah C Moore[SUP] 4 [/SUP], Anthony T Newall[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Respiratory syncytial virus (RSV) and influenza are important causes of disease in children and adults. In Australia, information on the burden of RSV in adults is particularly limited.
Methods: We used time series analysis to estimate respiratory, acute respiratory infection, pneumonia and influenza, and bronchiolitis hospitalisations attributable to RSV and influenza in Australia during 2009 through 2017. RSV and influenza-coded hospitalisations in <5-year-olds were used as proxies for relative weekly viral activity.
Results: From 2009 to 2017, the estimated all-age average annual rates of respiratory hospitalisations attributable to RSV and seasonal influenza (excluding 2009) were 54.8 (95% confidence interval [CI]: 20.1, 88.8) and 87.8 (95% CI: 74.5, 97.7) per 100,000, respectively. The highest estimated average annual RSV-attributable respiratory hospitalisation rate per 100,000 was 464.2 (95% CI: 285.9, 641.2) in <5-year-olds. For seasonal influenza, it was 521.6 (95% CI: 420.9, 600.0) in persons aged ≥75 years. In ≥75-year-olds, modelled estimates were approximately eight and two times the coded estimates for RSV and seasonal influenza, respectively.
Conclusions: RSV and influenza are major causes of hospitalisation in young children and older adults in Australia, with morbidity underestimated by hospital diagnosis codes.
Keywords: RSV hospitalisation; burden; epidemiology; influenza hospitalisation; regression modelling; time series analysis.
. 2022 Jun 30.
doi: 10.1111/irv.13003. Online ahead of print.
Modelled estimates of hospitalisations attributable to respiratory syncytial virus and influenza in Australia, 2009-2017
Allen L Nazareno[SUP] 1 2 [/SUP], David J Muscatello[SUP] 1 [/SUP], Robin M Turner[SUP] 3 [/SUP], James G Wood[SUP] 1 [/SUP], Hannah C Moore[SUP] 4 [/SUP], Anthony T Newall[SUP] 1 [/SUP]
Affiliations
- PMID: 35775106
- DOI: 10.1111/irv.13003
Abstract
Background: Respiratory syncytial virus (RSV) and influenza are important causes of disease in children and adults. In Australia, information on the burden of RSV in adults is particularly limited.
Methods: We used time series analysis to estimate respiratory, acute respiratory infection, pneumonia and influenza, and bronchiolitis hospitalisations attributable to RSV and influenza in Australia during 2009 through 2017. RSV and influenza-coded hospitalisations in <5-year-olds were used as proxies for relative weekly viral activity.
Results: From 2009 to 2017, the estimated all-age average annual rates of respiratory hospitalisations attributable to RSV and seasonal influenza (excluding 2009) were 54.8 (95% confidence interval [CI]: 20.1, 88.8) and 87.8 (95% CI: 74.5, 97.7) per 100,000, respectively. The highest estimated average annual RSV-attributable respiratory hospitalisation rate per 100,000 was 464.2 (95% CI: 285.9, 641.2) in <5-year-olds. For seasonal influenza, it was 521.6 (95% CI: 420.9, 600.0) in persons aged ≥75 years. In ≥75-year-olds, modelled estimates were approximately eight and two times the coded estimates for RSV and seasonal influenza, respectively.
Conclusions: RSV and influenza are major causes of hospitalisation in young children and older adults in Australia, with morbidity underestimated by hospital diagnosis codes.
Keywords: RSV hospitalisation; burden; epidemiology; influenza hospitalisation; regression modelling; time series analysis.