tetano
Editor, Senior Moderator
Afr Health Sci. 2018 Dec;18(4):1134-1143. doi: 10.4314/ahs.v18i4.34.
[h=1]Influenza virus A (H1 and H3) and B co-circulation among patient presenting with acute respiratory tract infection in Ibadan, Nigeria.[/h] Odun-Ayo F[SUP]1[/SUP], Odaibo G[SUP]1[/SUP], Olaleye D[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]Background:[/h] Influenza is an acute respiratory disease that continues to cause global epidemics and pandemics in human with significant mortality and morbidity.
[h=4]Objectives:[/h] This study was designed to identify the circulating influenza virus in Ibadan, Nigeria during the 2006/2007 season.
[h=4]Methods:[/h] Throat swab samples were collected from patients presenting with acute respiratory tract infection at the Out-Patient Departments of major hospitals in Ibadan over a period of seven months from November 2006 to May 2007. Isolation of influenza virus was performed using Madin-Darby Canine Kidney cell line and 10 days old chicken embryonated egg. Isolates was identified by haemagglutination and haemagglutination-inhibition assays using selected CDC Influenza reference antisera (A, B, subtype H1 and H3).
[h=4]Results:[/h] Out of 128 patients tested, 21(16.4%) yielded positive for virus isolation. Identification of the isolates showed that 19(14.8%) were positive for influenza virus out of which 11(8.6%) and 8(6.2%) were influenza A and B viruses respectively. Influenza A virus 6(4.7%) were subtype H1; 4(3.1%) were co-subtype H1 and H3; and 1(0.8%) was not inhibited by subtype H1 and H3.
[h=4]Conclusion:[/h] The circulation of influenza virus A and B in this study is important to contributing knowledge and data to influenza epidemiology and surveillance in Nigeria.
[h=4]KEYWORDS:[/h] Influenza A; Nigeria; haemagglutination; isolation
PMID: 30766579 PMCID: PMC6354865 DOI: 10.4314/ahs.v18i4.34
Free PMC Article
[h=1]Influenza virus A (H1 and H3) and B co-circulation among patient presenting with acute respiratory tract infection in Ibadan, Nigeria.[/h] Odun-Ayo F[SUP]1[/SUP], Odaibo G[SUP]1[/SUP], Olaleye D[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]Background:[/h] Influenza is an acute respiratory disease that continues to cause global epidemics and pandemics in human with significant mortality and morbidity.
[h=4]Objectives:[/h] This study was designed to identify the circulating influenza virus in Ibadan, Nigeria during the 2006/2007 season.
[h=4]Methods:[/h] Throat swab samples were collected from patients presenting with acute respiratory tract infection at the Out-Patient Departments of major hospitals in Ibadan over a period of seven months from November 2006 to May 2007. Isolation of influenza virus was performed using Madin-Darby Canine Kidney cell line and 10 days old chicken embryonated egg. Isolates was identified by haemagglutination and haemagglutination-inhibition assays using selected CDC Influenza reference antisera (A, B, subtype H1 and H3).
[h=4]Results:[/h] Out of 128 patients tested, 21(16.4%) yielded positive for virus isolation. Identification of the isolates showed that 19(14.8%) were positive for influenza virus out of which 11(8.6%) and 8(6.2%) were influenza A and B viruses respectively. Influenza A virus 6(4.7%) were subtype H1; 4(3.1%) were co-subtype H1 and H3; and 1(0.8%) was not inhibited by subtype H1 and H3.
[h=4]Conclusion:[/h] The circulation of influenza virus A and B in this study is important to contributing knowledge and data to influenza epidemiology and surveillance in Nigeria.
[h=4]KEYWORDS:[/h] Influenza A; Nigeria; haemagglutination; isolation
PMID: 30766579 PMCID: PMC6354865 DOI: 10.4314/ahs.v18i4.34
Free PMC Article