tetano
Editor, Senior Moderator
Clin Kidney J. 2015 Jun;8(3):325-8. doi: 10.1093/ckj/sfv027. Epub 2015 May 6.
[h=1]Influenza virus vaccination and kidney graft rejection: causality or coincidence.[/h] Fischer AS[SUP]1[/SUP], M?ller BK[SUP]2[/SUP], Krag S[SUP]3[/SUP], Jespersen B[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza can cause significant morbidity and mortality in renal transplant recipients especially with a high rate of lower respiratory disease. Annual influenza vaccination is therefore recommended to renal transplant recipients. We report the first three cases of acute kidney injury in renal transplant recipients following influenza vaccination that all led to graft loss. They all had different native diseases and were all vaccinated in the same season of 2009-10. The time span from vaccination to decline of kidney function is shorter than the time to diagnosis since the three patients only had blood tests every 3 months or when symptoms became severe. These reports do not justify a change of current recommendations regarding influenza vaccination in renal transplant recipients, but they support the continued attention and registration of vaccinations to monitor side effects.
[h=4]KEYWORDS:[/h] acute kidney injury; influenza vaccination; kidney graft rejection; renal transplant recipient
PMID: 26034595 [PubMed] PMCID: PMC4440474 Free PMC Article
[h=1]Influenza virus vaccination and kidney graft rejection: causality or coincidence.[/h] Fischer AS[SUP]1[/SUP], M?ller BK[SUP]2[/SUP], Krag S[SUP]3[/SUP], Jespersen B[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza can cause significant morbidity and mortality in renal transplant recipients especially with a high rate of lower respiratory disease. Annual influenza vaccination is therefore recommended to renal transplant recipients. We report the first three cases of acute kidney injury in renal transplant recipients following influenza vaccination that all led to graft loss. They all had different native diseases and were all vaccinated in the same season of 2009-10. The time span from vaccination to decline of kidney function is shorter than the time to diagnosis since the three patients only had blood tests every 3 months or when symptoms became severe. These reports do not justify a change of current recommendations regarding influenza vaccination in renal transplant recipients, but they support the continued attention and registration of vaccinations to monitor side effects.
[h=4]KEYWORDS:[/h] acute kidney injury; influenza vaccination; kidney graft rejection; renal transplant recipient
PMID: 26034595 [PubMed] PMCID: PMC4440474 Free PMC Article