tetano
Editor, Senior Moderator
Am J Med Sci. 2019 Oct;358(4):289-293. doi: 10.1016/j.amjms.2019.07.014. Epub 2019 Aug 1.
[h=1]Influenza With Community-Associated Methicillin-Resistant Staphylococcus Aureus Pneumonia.[/h] Liu CW[SUP]1[/SUP], Lin SP[SUP]2[/SUP], Wang WY[SUP]3[/SUP], Huang YH[SUP]4[/SUP].
[h=3]Author information[/h] 1 Department of Internal Medicine and. 2 Department of Internal Medicine and; Division of Infectious Diseases, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China. 3 Department of Internal Medicine, Feng-Yuan Hospital, Ministry of Health and Welfare, Taichung, Taiwan, Republic of China. 4 Department of Internal Medicine and; Department of Critical Care Medicine and; Division of Chest Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China; Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan, Republic of China. Electronic address: waynehuang0622@gmail.com.
[h=3]Abstract[/h] Patients with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia have poor clinical outcomes and high frequency of mortality, especially in patents with postinfluenza infection. Herein, we report a case of community-acquired pneumonia with multiple organ failure in a 51-year-old patient with initial presentation of flu-like symptoms. The influenza rapid test from the specimen of nasopharyngeal swab was positive for type B influenza virus and was confirmed by real-time polymerase chain reaction. Gram stain of bronchoalveolar lavage fluid revealed gram positive cocci in group. Both sputum and blood culture yielded MRSA. We identified the CA-MRSA was staphylococcal cassette chromosome mec type IV strain carried Panton-Valentine leukocidin gene. The patient made a complete recovery following an 8-week treatment course of linezolid and was discharged with independent daily activity. According to our experience, linezolid may be a reasonable treatment choice for CA-MRSA pneumonia due to the virulence of exotoxins.
Copyright ? 2019 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
[h=4]KEYWORDS:[/h] Community-associated methicillin-resistant Staphylococcus aureus; Influenza; Linezolid; Panton-Valentine leucocidin
PMID: 31543102 DOI: 10.1016/j.amjms.2019.07.014
[h=1]Influenza With Community-Associated Methicillin-Resistant Staphylococcus Aureus Pneumonia.[/h] Liu CW[SUP]1[/SUP], Lin SP[SUP]2[/SUP], Wang WY[SUP]3[/SUP], Huang YH[SUP]4[/SUP].
[h=3]Author information[/h] 1 Department of Internal Medicine and. 2 Department of Internal Medicine and; Division of Infectious Diseases, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China. 3 Department of Internal Medicine, Feng-Yuan Hospital, Ministry of Health and Welfare, Taichung, Taiwan, Republic of China. 4 Department of Internal Medicine and; Department of Critical Care Medicine and; Division of Chest Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China; Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan, Republic of China. Electronic address: waynehuang0622@gmail.com.
[h=3]Abstract[/h] Patients with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia have poor clinical outcomes and high frequency of mortality, especially in patents with postinfluenza infection. Herein, we report a case of community-acquired pneumonia with multiple organ failure in a 51-year-old patient with initial presentation of flu-like symptoms. The influenza rapid test from the specimen of nasopharyngeal swab was positive for type B influenza virus and was confirmed by real-time polymerase chain reaction. Gram stain of bronchoalveolar lavage fluid revealed gram positive cocci in group. Both sputum and blood culture yielded MRSA. We identified the CA-MRSA was staphylococcal cassette chromosome mec type IV strain carried Panton-Valentine leukocidin gene. The patient made a complete recovery following an 8-week treatment course of linezolid and was discharged with independent daily activity. According to our experience, linezolid may be a reasonable treatment choice for CA-MRSA pneumonia due to the virulence of exotoxins.
Copyright ? 2019 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
[h=4]KEYWORDS:[/h] Community-associated methicillin-resistant Staphylococcus aureus; Influenza; Linezolid; Panton-Valentine leucocidin
PMID: 31543102 DOI: 10.1016/j.amjms.2019.07.014