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Influenzavirus B-associated acute benign myalgia cruris: An outbreak report and review of the literature

tetano

Editor, Senior Moderator
Neuromuscul Disord. 2014 Jan 4. pii: S0960-8966(13)01051-1. doi: 10.1016/j.nmd.2013.12.009. [Epub ahead of print]
Influenzavirus B-associated acute benign myalgia cruris: An outbreak report and review of the literature.
Ferrarini A1, Lava SA1, Simonetti GD1, Ramelli GP1, Bianchetti MG2; on behalf of the Swiss Italian Society of Pediatrics.
Author information
Abstract

Acute benign myalgia cruris is characterized by transient bilateral calf pain that leads to difficulty walking. A regional outbreak of influenza virus B-associated myalgia cruris was observed during the seasonal influenza outbreak observed in Switzerland from week 1 to 13 of 2013. We performed a prospective case finding among the Swiss-Italian pediatric emergency units and pediatricians. A review of the literature was also performed. The diagnosis of myalgia cruris was made in 49 Swiss-Italian children aged 3.0-14years (♂:♀=1.7). Flu-like symptoms were resolving when bilateral calf pain began that remitted over ⩽7days. The creatine kinase-level, assessed in 28 patients, was elevated in 25. Nose swabs were positive for influenza virus B in 13 out of 14 cases. The blood cell count, measured in 41 cases, disclosed leucopenia in 12 and thrombocytopenia in 3. The review of the literature found 10 outbreaks of ⩾10 cases of influenza virus B-associated myalgia cruris, which included a total of 203 patients with a mean age of 7.3years and a ♂:♀ ratio of 2.0. In conclusion influenza virus B caused a large Swiss-Italian outbreak of myalgia cruris. Our outbreak and the literature indicate that influenza virus B-associated myalgia cruris affects preschool- and school-aged children, primarily boys.

Copyright ? 2013 Elsevier B.V. All rights reserved.
KEYWORDS:

Acute benign myalgia cruris, Acute toe walking, Benign childhood myositis, Bottom shuffling, Frankenstein walk, Influenza virus B, Review

PMID:
24530048
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24530048
 
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