tetano
Editor, Senior Moderator
Int J Environ Res Public Health
. 2021 Jun 11;18(12):6353.
doi: 10.3390/ijerph18126353.
Sero-Prevalence of SARS-CoV-2 Antibodies in High-Risk Populations in Vietnam
Tasnim Hasan[SUP] 1 2 [/SUP], Thach Ngoc Pham[SUP] 3 [/SUP], Thu Anh Nguyen[SUP] 2 [/SUP], Hien Thi Thu Le[SUP] 2 [/SUP], Duyet Van Le[SUP] 3 [/SUP], Thuy Thi Dang[SUP] 3 [/SUP], Trang Dinh Van[SUP] 3 [/SUP], Yen Ngoc Pham[SUP] 2 [/SUP], Ha Viet Nguyen[SUP] 2 [/SUP], Giang Linh Tran[SUP] 2 [/SUP], Van Thi Cam Nguyen[SUP] 2 [/SUP], Thanh Trung Nguyen[SUP] 2 [/SUP], Viet Quang Truong[SUP] 4 [/SUP], Than Huu Dao[SUP] 4 [/SUP], Chung Thanh Le[SUP] 5 [/SUP], Nam Tan Truong[SUP] 5 [/SUP], Hoang Trung Vo[SUP] 6 [/SUP], Phuc Thanh Le[SUP] 7 [/SUP], Thao Thanh Nguyen[SUP] 8 [/SUP], Vinh Van Luu[SUP] 8 [/SUP], Vinh Dai Nguyen[SUP] 9 [/SUP], Brett G Toelle[SUP] 1 2 10 [/SUP], Guy B Marks[SUP] 2 11 [/SUP], Greg J Fox[SUP] 1 2 [/SUP]
Affiliations
Abstract
As a response to the coronavirus disease 2019 (COVID-19) pandemic, Vietnam enforced strict quarantine, contact tracing and physical distancing policies resulting in one of the lowest numbers of individuals infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) globally. This study aimed to determine the prevalence of SARS-CoV-2 antibody positivity among high-risk populations in Vietnam. A prevalence survey was undertaken within four communities in Vietnam, where at least two COVID-19 cases had been confirmed. Participants were classified according to the location of exposure: household contacts, close contacts, community members, and healthcare workers (HCWs) responsible for treating COVID-19 cases. Participants completed a baseline questionnaire and SARS-CoV-2 IgG antibodies were quantified using a commercial assay. A total of 3049 community members and 149 health care workers consented to the study. Among 13 individuals who were seropositive (0.4%), five household contacts (5/27, 18.5%), one close contact (1/53, 1.9%), and seven community members (7/2954, 0.2%) had detectable SARS-CoV-2 antibodies. All HCWs were negative for SARS-CoV-2 antibodies. Participants were tested a median of 15.1 (interquartile range from 14.9 to 15.2) weeks after exposure. Our study found a low prevalence of SARS-CoV-2 antibodies in high-risk communities and healthcare workers in communities in Vietnam with known COVID-19 cases.
Keywords: COVID-19; SARS-CoV-2; Vietnam; seroprevalence.
. 2021 Jun 11;18(12):6353.
doi: 10.3390/ijerph18126353.
Sero-Prevalence of SARS-CoV-2 Antibodies in High-Risk Populations in Vietnam
Tasnim Hasan[SUP] 1 2 [/SUP], Thach Ngoc Pham[SUP] 3 [/SUP], Thu Anh Nguyen[SUP] 2 [/SUP], Hien Thi Thu Le[SUP] 2 [/SUP], Duyet Van Le[SUP] 3 [/SUP], Thuy Thi Dang[SUP] 3 [/SUP], Trang Dinh Van[SUP] 3 [/SUP], Yen Ngoc Pham[SUP] 2 [/SUP], Ha Viet Nguyen[SUP] 2 [/SUP], Giang Linh Tran[SUP] 2 [/SUP], Van Thi Cam Nguyen[SUP] 2 [/SUP], Thanh Trung Nguyen[SUP] 2 [/SUP], Viet Quang Truong[SUP] 4 [/SUP], Than Huu Dao[SUP] 4 [/SUP], Chung Thanh Le[SUP] 5 [/SUP], Nam Tan Truong[SUP] 5 [/SUP], Hoang Trung Vo[SUP] 6 [/SUP], Phuc Thanh Le[SUP] 7 [/SUP], Thao Thanh Nguyen[SUP] 8 [/SUP], Vinh Van Luu[SUP] 8 [/SUP], Vinh Dai Nguyen[SUP] 9 [/SUP], Brett G Toelle[SUP] 1 2 10 [/SUP], Guy B Marks[SUP] 2 11 [/SUP], Greg J Fox[SUP] 1 2 [/SUP]
Affiliations
- PMID: 34208212
- DOI: 10.3390/ijerph18126353
Abstract
As a response to the coronavirus disease 2019 (COVID-19) pandemic, Vietnam enforced strict quarantine, contact tracing and physical distancing policies resulting in one of the lowest numbers of individuals infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) globally. This study aimed to determine the prevalence of SARS-CoV-2 antibody positivity among high-risk populations in Vietnam. A prevalence survey was undertaken within four communities in Vietnam, where at least two COVID-19 cases had been confirmed. Participants were classified according to the location of exposure: household contacts, close contacts, community members, and healthcare workers (HCWs) responsible for treating COVID-19 cases. Participants completed a baseline questionnaire and SARS-CoV-2 IgG antibodies were quantified using a commercial assay. A total of 3049 community members and 149 health care workers consented to the study. Among 13 individuals who were seropositive (0.4%), five household contacts (5/27, 18.5%), one close contact (1/53, 1.9%), and seven community members (7/2954, 0.2%) had detectable SARS-CoV-2 antibodies. All HCWs were negative for SARS-CoV-2 antibodies. Participants were tested a median of 15.1 (interquartile range from 14.9 to 15.2) weeks after exposure. Our study found a low prevalence of SARS-CoV-2 antibodies in high-risk communities and healthcare workers in communities in Vietnam with known COVID-19 cases.
Keywords: COVID-19; SARS-CoV-2; Vietnam; seroprevalence.