Int J Infect Dis . A Case Report of Newborn Infant with Severe COVID-19 in Mexico: Detection of SARS-CoV-2 in Human Breast Milk and Stool

[tetano]

Int J Infect Dis


. 2020 Aug 26;S1201-9712(20)30684-6.
doi: 10.1016/j.ijid.2020.08.055. Online ahead of print.
A Case Report of Newborn Infant with Severe COVID-19 in Mexico: Detection of SARS-CoV-2 in Human Breast Milk and Stool


Alejandro Hinojosa-Velasco[SUP] 1 [/SUP], Paloma V Bobadilla-Montes de Oca[SUP] 1 [/SUP], Lidia E Garc?a-Sosa[SUP] 1 [/SUP], J Gabriel Mendoza-Dur?n[SUP] 2 [/SUP], Mar?a J P?rez-M?ndez[SUP] 3 [/SUP], Eduardo D?vila-Gonz?lez[SUP] 3 [/SUP], Dolores G Ram?rez-Hern?ndez[SUP] 3 [/SUP], Jaime Garc?a-Mena[SUP] 4 [/SUP], Paola Z?rate-Segura[SUP] 5 [/SUP], Jos? Manuel Reyes-Ruiz[SUP] 6 [/SUP], Fernando Bastida-Gonz?lez[SUP] 7 [/SUP]



Affiliations

• PMID: 32860950
• DOI: 10.1016/j.ijid.2020.08.055

Abstract

Although COVID-19 in pregnant women and their neonates has been demonstrated, there is not enough evidence about how this vertical transmission occurs. This report describes SARS-CoV-2 infection in a 21-year-old mother-son duo at the time of birth, focusing on the viral RNA detection in the stool of both, and the human breast milk.

Keywords: COVID-19; SARS-CoV-2; coronavirus; human milk; neonate; vertical transmission.

 

[JJackson]

Yet another paper with a misleading title. SARS-CoV-2 was not found in either breast milk or stool samples! RNA from the virus was, these titles are click bait. 'Massive fire in London' makes a great headline worthy of one of our tabloids but when read a better title might be archaeologists find evidence of extent of the 'Great fire of London' of 1666.

 

[Mary Wilson]

August 19, 2020

Evaluation for SARS-CoV-2 in Breast Milk From 18 Infected Women

Christina Chambers, PhD, MPH[SUP]1[/SUP]; Paul Krogstad, MD[SUP]2[/SUP]; Kerri Bertrand, MPH[SUP]1[/SUP]; et al

JAMA. Published online August 19, 2020. doi:10.1001/jama.2020.15580

...
Results

Between March 27 and May 6, 2020, we enrolled 18 women who had confirmed SARS-CoV-2 infection (77.7% White non-Hispanic, mean age 34.4 years [SD, 5.2 years]). Their offspring ranged in age from newborn to 19 months. Women provided between 1 and 12 samples, with a total of 64 samples collected at varying time points before and after the positive SARS-CoV-2 RT-PCR test result. All but 1 woman had symptomatic disease (Figure). One breast milk sample had detectable SARS-CoV-2 RNA. The positive sample was collected on the day of symptom onset; however, 1 sample taken 2 days prior to symptom onset and 2 samples collected 12 and 41 days later tested negative for viral RNA. The breastfed infant was not tested. No replication-competent virus was detectable in any sample, including the sample that tested positive for viral RNA.
...

https://jamanetwork.com/journals/jama/fullarticle/2769825

 

[JJackson]

Much better. The title accurately describes the contents, they found RNA in one of the 64 samples and NO replication-competent virions.