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Int J Infect Dis . Epidemiological and Clinical Characteristics of Coronavirus Disease 2019 in Daegu, South Korea

tetano

Editor, Senior Moderator
Int J Infect Dis


. 2020 Jul 20;S1201-9712(20)30561-0.
doi: 10.1016/j.ijid.2020.07.017. Online ahead of print.
Epidemiological and Clinical Characteristics of Coronavirus Disease 2019 in Daegu, South Korea


Ji Yeon Lee[SUP] 1 [/SUP], Seung Wan Hong[SUP] 2 [/SUP], Miri Hyun[SUP] 1 [/SUP], Jae Seok Park[SUP] 3 [/SUP], Jae Hyuck Lee[SUP] 4 [/SUP], Young Sung Suh[SUP] 2 [/SUP], Dae Hyun Kim[SUP] 2 [/SUP], Seong-Wook Han[SUP] 5 [/SUP], Chi-Heum Cho[SUP] 6 [/SUP], Hyun Ah Kim[SUP] 7 [/SUP]



Affiliations

Abstract

Objectives: The Coronavirus Disease 2019 (COVID-19) outbreak simultaneously occurred at a church and a long-term care facility in Daegu. This study aimed to investigate the epidemiological characteristics of COVID-19 and factors related to severe outcomes.
Methods: We enrolled all inpatients diagnosed with COVID-19 between February 21 and April 2, 2020 in Daegu Dongsan Hospital, South Korea. We analyzed their clinical and demographic data, laboratory parameters, radiological findings, symptoms, and treatment outcomes.
Results: Of 694 patients, severe cases accounted for 19.7% (137 patients). No severe case was observed among patients aged ≤19 years. Hypertension was the most common co-morbidity (27%), and cough was the most common symptom (59%). Besides, asymptomatic patients accounted for 14.4% of cases. Lymphopenia, lactate dehydrogenase, C-reactive protein, and albumin were associated with severe outcomes. The first outbreak was mostly associated with younger age groups, and asymptomatic patients mostly showed mild progression. In the second outbreak involving a long-term care facility, both the number of severe patients and the mortality rate were high.
Conclusions: The overall mortality in Daegu was low, which might have resulted from large scale mass screening to detect patients and starting appropriate treatment, including hospitalization for severe cases, and quarantine for asymptomatic patients.

Keywords: Coronavirus Disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemiology.
 
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