tetano
Editor, Senior Moderator
Int J Infect Dis
. 2023 Nov 18:S1201-9712(23)00780-4.
doi: 10.1016/j.ijid.2023.11.019. Online ahead of print. Prevalence of respiratory viruses among hospitalized children with lower respiratory tract infections during the COVID-19 pandemic in Wuhan, China
Ying Li[SUP] 1 [/SUP], Zhiyong Wu[SUP] 2 [/SUP], Yi Yan[SUP] 3 [/SUP], Yue Shi[SUP] 3 [/SUP], Jiaming Huang[SUP] 2 [/SUP], Hui Du[SUP] 4 [/SUP], Qing Du[SUP] 4 [/SUP], Yang Li[SUP] 4 [/SUP], Yaxin Lin[SUP] 4 [/SUP], Di Liu[SUP] 2 [/SUP], Xiaoxia Lu[SUP] 5 [/SUP]
Affiliations
Objectives: We aimed to investigate the continuous changes in respiratory virus epidemics in hospitalized children with lower respiratory tract infections (LRTIs) persisting from January 2019 to December 2022 in Wuhan, China.
Methods: We retrospectively enrolled children with LRTIs admitted to the Wuhan Children's Hospital. Specimens were nasopharyngeal aspirates which had been collected and detected the following microorganisms with direct immunofluorescence: influenza virus types A and B, respiratory syncytial virus, parainfluenza virus types 1-3, and adenovirus. We also analyzed demographic data and laboratory test results.
Results: A total of 22,660 patients were enrolled. The total virus detection rate in 2019, 2021, and 2022 significantly declined gradually (36.96% vs. 29.47% vs. 22.62%, p value <0.001). All the detected viruses did not follow previously observed seasonal patterns during the COVID-19 pandemic. Children hospitalized for LRTIs were older during the COVID-19 pandemic in contrast to the pre-period, particularly notable in cases attributed to RSV and PIV3 infections.
Conclusions: This work adds to our knowledge of the epidemiology characteristics of respiratory viruses spanning the COVID-19 pandemic among children with LRTIs. The circulation of respiratory viruses changed consistently, and active LRTIs surveillance in children remains critical for defining the healthcare burden of respiratory viruses.
Keywords: COVID-19; LRTIs; Respiratory viruses; children; epidemiology.
. 2023 Nov 18:S1201-9712(23)00780-4.
doi: 10.1016/j.ijid.2023.11.019. Online ahead of print. Prevalence of respiratory viruses among hospitalized children with lower respiratory tract infections during the COVID-19 pandemic in Wuhan, China
Ying Li[SUP] 1 [/SUP], Zhiyong Wu[SUP] 2 [/SUP], Yi Yan[SUP] 3 [/SUP], Yue Shi[SUP] 3 [/SUP], Jiaming Huang[SUP] 2 [/SUP], Hui Du[SUP] 4 [/SUP], Qing Du[SUP] 4 [/SUP], Yang Li[SUP] 4 [/SUP], Yaxin Lin[SUP] 4 [/SUP], Di Liu[SUP] 2 [/SUP], Xiaoxia Lu[SUP] 5 [/SUP]
Affiliations
- PMID: 37984762
- DOI: 10.1016/j.ijid.2023.11.019
Objectives: We aimed to investigate the continuous changes in respiratory virus epidemics in hospitalized children with lower respiratory tract infections (LRTIs) persisting from January 2019 to December 2022 in Wuhan, China.
Methods: We retrospectively enrolled children with LRTIs admitted to the Wuhan Children's Hospital. Specimens were nasopharyngeal aspirates which had been collected and detected the following microorganisms with direct immunofluorescence: influenza virus types A and B, respiratory syncytial virus, parainfluenza virus types 1-3, and adenovirus. We also analyzed demographic data and laboratory test results.
Results: A total of 22,660 patients were enrolled. The total virus detection rate in 2019, 2021, and 2022 significantly declined gradually (36.96% vs. 29.47% vs. 22.62%, p value <0.001). All the detected viruses did not follow previously observed seasonal patterns during the COVID-19 pandemic. Children hospitalized for LRTIs were older during the COVID-19 pandemic in contrast to the pre-period, particularly notable in cases attributed to RSV and PIV3 infections.
Conclusions: This work adds to our knowledge of the epidemiology characteristics of respiratory viruses spanning the COVID-19 pandemic among children with LRTIs. The circulation of respiratory viruses changed consistently, and active LRTIs surveillance in children remains critical for defining the healthcare burden of respiratory viruses.
Keywords: COVID-19; LRTIs; Respiratory viruses; children; epidemiology.