tetano
Editor, Senior Moderator
Epidemiol Infect. 2018 Jul 26:1-9. doi: 10.1017/S0950268818002017. [Epub ahead of print]
[h=1]Interactive effects of age and respiratory virus on severe lower respiratory infection.[/h] Prasad N[SUP]1[/SUP], Trenholme AA[SUP]2[/SUP], Huang QS[SUP]1[/SUP], Thompson MG[SUP]3[/SUP], Pierse N[SUP]4[/SUP], Widdowson MA[SUP]3[/SUP], Wood T[SUP]1[/SUP], Seeds R[SUP]1[/SUP], Taylor S[SUP]2[/SUP], Grant CC[SUP]5[/SUP], Newbern EC[SUP]1[/SUP]; SHIVERS team.
[h=3]Author information[/h]
[h=3]Abstract[/h] We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.
[h=4]KEYWORDS:[/h] ADV adenovirus; ALRI acute lower respiratory infection; ICU intensive care unit admission; LOS hospital length of stay; RSV respiratory syncytial virus; children; respiratory virus; severe ALRI
PMID: 30047350 DOI: 10.1017/S0950268818002017
[h=1]Interactive effects of age and respiratory virus on severe lower respiratory infection.[/h] Prasad N[SUP]1[/SUP], Trenholme AA[SUP]2[/SUP], Huang QS[SUP]1[/SUP], Thompson MG[SUP]3[/SUP], Pierse N[SUP]4[/SUP], Widdowson MA[SUP]3[/SUP], Wood T[SUP]1[/SUP], Seeds R[SUP]1[/SUP], Taylor S[SUP]2[/SUP], Grant CC[SUP]5[/SUP], Newbern EC[SUP]1[/SUP]; SHIVERS team.
[h=3]Author information[/h]
[h=3]Abstract[/h] We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.
[h=4]KEYWORDS:[/h] ADV adenovirus; ALRI acute lower respiratory infection; ICU intensive care unit admission; LOS hospital length of stay; RSV respiratory syncytial virus; children; respiratory virus; severe ALRI
PMID: 30047350 DOI: 10.1017/S0950268818002017