tetano
Editor, Senior Moderator
Interdiscip Neurosurg
. 2022 Sep;29:101599.
doi: 10.1016/j.inat.2022.101599. Epub 2022 Jun 6.
Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases
Mahmoud M Taha[SUP] 1 [/SUP], Mazen M Taha[SUP] 2 [/SUP], Hassan A Al Menshawy[SUP] 3 [/SUP], Ahmad M Elsharkawy[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Initially, novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) was considered primarily a respiratory pathogen. However, with time it has behaved as a virus with the potential to cause multi-system involvement, including neurological manifestations which varies from acute to subacute onset of headache, seizures, a decrease of consciousness, and paralysis.
Case description: Two cases of cerebral sinus venous thrombosis in COVID-19 patients were reported, following respiratory disorders, which was triggered by the SARS-CoV-2 infection. The first patient, presented with a decrease in level of consciousness and hemiparesis, was 23 years old female having no history of previous medical co-morbidities. The latter case, 21 years old woman showed less severe presentations of COVID-19 associated with headache, vomiting and papilledema. These two cases marvellously improved with no neurological deficit with aggressive course of anticoagulation.
Conclusion: CVST should be suspected in COVID-19 patients presenting with headache, paralysis, aphasia or seizures. The high mortality rate of CVST in COVID-19 infection warrants a high index of suspicion from physicians, and early treatment with anticoagulation should be initiated.
Keywords: Cerebral venous sinus thrombosis (CVST); Corona virus disease 2019 (COVID-19); Neurologic manifestations; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Venous thrombotic events (VTE).
. 2022 Sep;29:101599.
doi: 10.1016/j.inat.2022.101599. Epub 2022 Jun 6.
Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases
Mahmoud M Taha[SUP] 1 [/SUP], Mazen M Taha[SUP] 2 [/SUP], Hassan A Al Menshawy[SUP] 3 [/SUP], Ahmad M Elsharkawy[SUP] 1 [/SUP]
Affiliations
- PMID: 35692246
- PMCID: PMC9167686
- DOI: 10.1016/j.inat.2022.101599
Abstract
Background: Initially, novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) was considered primarily a respiratory pathogen. However, with time it has behaved as a virus with the potential to cause multi-system involvement, including neurological manifestations which varies from acute to subacute onset of headache, seizures, a decrease of consciousness, and paralysis.
Case description: Two cases of cerebral sinus venous thrombosis in COVID-19 patients were reported, following respiratory disorders, which was triggered by the SARS-CoV-2 infection. The first patient, presented with a decrease in level of consciousness and hemiparesis, was 23 years old female having no history of previous medical co-morbidities. The latter case, 21 years old woman showed less severe presentations of COVID-19 associated with headache, vomiting and papilledema. These two cases marvellously improved with no neurological deficit with aggressive course of anticoagulation.
Conclusion: CVST should be suspected in COVID-19 patients presenting with headache, paralysis, aphasia or seizures. The high mortality rate of CVST in COVID-19 infection warrants a high index of suspicion from physicians, and early treatment with anticoagulation should be initiated.
Keywords: Cerebral venous sinus thrombosis (CVST); Corona virus disease 2019 (COVID-19); Neurologic manifestations; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Venous thrombotic events (VTE).