tetano
Editor, Senior Moderator
Intern Emerg Med
. 2021 Jun 30.
doi: 10.1007/s11739-021-02795-9. Online ahead of print.
Associations between CT pulmonary opacity score on admission and clinical characteristics and outcomes in patients with COVID-19
Huanyuan Luo[SUP] #[/SUP][SUP] 1 [/SUP], Yuancheng Wang[SUP] #[/SUP][SUP] 2 [/SUP], Songqiao Liu[SUP] #[/SUP][SUP] 3 [/SUP], Ruoling Chen[SUP] 4 [/SUP], Tao Chen[SUP] 1 [/SUP], Yi Yang[SUP] 3 [/SUP], Duolao Wang[SUP] 5 [/SUP], Shenghong Ju[SUP] 6 [/SUP]
Affiliations
Abstract
This study investigated associations between chest computed tomography (CT) pulmonary opacity score on admission and clinical features and outcomes in COVID-19 patients. The retrospective multi-center cohort study included 496 COVID-19 patients in Jiangsu province, China diagnosed as of March 15, 2020. Patients were divided into four groups based on the quartile of pulmonary opacity score: ≤ 5%, 6-20%, 21-40% and 41% +. CT pulmonary opacity score was independently associated with age, single onset, fever, cough, peripheral capillary oxygen saturation, lymphocyte count, platelet count, albumin level, C-reactive protein (CRP) level and fibrinogen level on admission. Patients with score ≥ 41% had a dramatic increased risk of severe or critical illness [odds ratio (OR), 15.58, 95% confidence interval (CI) 3.82-63.53), intensive care unit (ICU)] admission (OR, 6.26, 95% CI 2.15-18.23), respiratory failure (OR, 19.49, 95% CI 4.55-83.40), and a prolonged hospital stay (coefficient, 2.59, 95% CI 0.46-4.72) compared to those with score ≤ 5%. CT pulmonary opacity score on admission, especially when ≥ 41%, was closely related to some clinical characteristics and was an independent predictor of disease severity, ICU admission, respiratory failure and long hospital stay in patients with COVID-19.
Keywords: 2019-nCoV; COVID-19; CT; Coronavirus; Prognosis; Pulmonary opacity.
. 2021 Jun 30.
doi: 10.1007/s11739-021-02795-9. Online ahead of print.
Associations between CT pulmonary opacity score on admission and clinical characteristics and outcomes in patients with COVID-19
Huanyuan Luo[SUP] #[/SUP][SUP] 1 [/SUP], Yuancheng Wang[SUP] #[/SUP][SUP] 2 [/SUP], Songqiao Liu[SUP] #[/SUP][SUP] 3 [/SUP], Ruoling Chen[SUP] 4 [/SUP], Tao Chen[SUP] 1 [/SUP], Yi Yang[SUP] 3 [/SUP], Duolao Wang[SUP] 5 [/SUP], Shenghong Ju[SUP] 6 [/SUP]
Affiliations
- PMID: 34191219
- DOI: 10.1007/s11739-021-02795-9
Abstract
This study investigated associations between chest computed tomography (CT) pulmonary opacity score on admission and clinical features and outcomes in COVID-19 patients. The retrospective multi-center cohort study included 496 COVID-19 patients in Jiangsu province, China diagnosed as of March 15, 2020. Patients were divided into four groups based on the quartile of pulmonary opacity score: ≤ 5%, 6-20%, 21-40% and 41% +. CT pulmonary opacity score was independently associated with age, single onset, fever, cough, peripheral capillary oxygen saturation, lymphocyte count, platelet count, albumin level, C-reactive protein (CRP) level and fibrinogen level on admission. Patients with score ≥ 41% had a dramatic increased risk of severe or critical illness [odds ratio (OR), 15.58, 95% confidence interval (CI) 3.82-63.53), intensive care unit (ICU)] admission (OR, 6.26, 95% CI 2.15-18.23), respiratory failure (OR, 19.49, 95% CI 4.55-83.40), and a prolonged hospital stay (coefficient, 2.59, 95% CI 0.46-4.72) compared to those with score ≤ 5%. CT pulmonary opacity score on admission, especially when ≥ 41%, was closely related to some clinical characteristics and was an independent predictor of disease severity, ICU admission, respiratory failure and long hospital stay in patients with COVID-19.
Keywords: 2019-nCoV; COVID-19; CT; Coronavirus; Prognosis; Pulmonary opacity.