tetano
Editor, Senior Moderator
Intern Med
. 2025 Apr 19.
doi: 10.2169/internalmedicine.5283-25. Online ahead of print. An autopsy for persistent coronavirus disease 2019 pneumonia during follicular lymphoma treatment: A case report
Hikaru Mamizu[SUP] 1 [/SUP], Jun Tsuji[SUP] 1 [/SUP], Morihiro Kumagai[SUP] 1 [/SUP], Chika Kuwana[SUP] 1 [/SUP], Masanori Miyagatani[SUP] 1 [/SUP], Maiko Mamizu[SUP] 1 [/SUP], Daisuke Ishikawa[SUP] 1 [/SUP], Hidenori Kawakami[SUP] 1 [/SUP], Toshiki Furukawa[SUP] 1 [/SUP], Takashi Ishida[SUP] 1 [/SUP], Chizuru Kaneko[SUP] 2 [/SUP], Takeshi Sakai[SUP] 2 [/SUP]
Affiliations
A 66-year-old man who was receiving treatment for B-cell non-Hodgkin lymphoma presented with fever. He tested positive for severe acute respiratory syndrome coronavirus 2 antigen. Chest computed tomography (CT) revealed pneumonia. Therefore, remdesivir was administered to the patient. However, steroid pulse therapy was initiated owing to the lack of any symptom improvement and a worsening of the CT findings. The patient developed recurrent fever following a reduction in the steroid dose. His respiratory condition gradually worsened, and he eventually died. Autopsy revealed diffuse alveolar damage. In high-risk patients with hematologic malignancy, COVID-19 vaccination should be repeated at shorter intervals to avoid increasing the viral load during the COVID-19 infection.
Keywords: bendamustine; coronavirus disease 2019 (COVID-19); follicular lymphoma; obinutuzumab; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
. 2025 Apr 19.
doi: 10.2169/internalmedicine.5283-25. Online ahead of print. An autopsy for persistent coronavirus disease 2019 pneumonia during follicular lymphoma treatment: A case report
Hikaru Mamizu[SUP] 1 [/SUP], Jun Tsuji[SUP] 1 [/SUP], Morihiro Kumagai[SUP] 1 [/SUP], Chika Kuwana[SUP] 1 [/SUP], Masanori Miyagatani[SUP] 1 [/SUP], Maiko Mamizu[SUP] 1 [/SUP], Daisuke Ishikawa[SUP] 1 [/SUP], Hidenori Kawakami[SUP] 1 [/SUP], Toshiki Furukawa[SUP] 1 [/SUP], Takashi Ishida[SUP] 1 [/SUP], Chizuru Kaneko[SUP] 2 [/SUP], Takeshi Sakai[SUP] 2 [/SUP]
Affiliations
- PMID: 40254437
- DOI: 10.2169/internalmedicine.5283-25
A 66-year-old man who was receiving treatment for B-cell non-Hodgkin lymphoma presented with fever. He tested positive for severe acute respiratory syndrome coronavirus 2 antigen. Chest computed tomography (CT) revealed pneumonia. Therefore, remdesivir was administered to the patient. However, steroid pulse therapy was initiated owing to the lack of any symptom improvement and a worsening of the CT findings. The patient developed recurrent fever following a reduction in the steroid dose. His respiratory condition gradually worsened, and he eventually died. Autopsy revealed diffuse alveolar damage. In high-risk patients with hematologic malignancy, COVID-19 vaccination should be repeated at shorter intervals to avoid increasing the viral load during the COVID-19 infection.
Keywords: bendamustine; coronavirus disease 2019 (COVID-19); follicular lymphoma; obinutuzumab; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).