tetano
Editor, Senior Moderator
Intern Med
. 2020 Sep 5.
doi: 10.2169/internalmedicine.5697-20. Online ahead of print.
Coronavirus Disease 2019 Complicated by Multiple Simultaneous Intracerebral Hemorrhages
Ryota Motoie[SUP] 1 [/SUP], Masaya Akai[SUP] 2 [/SUP], Takahiro Kitahara[SUP] 1 [/SUP], Hisaji Imamura[SUP] 3 [/SUP], Takeshi Tanabe[SUP] 4 [/SUP], Katsuhiko Sarazawa[SUP] 5 [/SUP], Seiichiro Takano[SUP] 3 [/SUP], Hiroki Toda[SUP] 1 [/SUP], Kazuto Komatsu[SUP] 6 [/SUP]
Affiliations
Abstract
The relationship between coronavirus disease 2019 (COVID-19) and intracerebral hemorrhage remains unclear. We herein report a case of severe COVID-19 pneumonia complicated by multiple simultaneous intracerebral hemorrhages (MSICH). The patient died eight days after the episode of MSICH. No apparent coagulopathy was observed; however, extracorporeal membrane oxygenation and anticoagulation might have caused the occurrence of MSICH. Laboratory findings showed hypercoagulability, suggesting that thrombotic etiologies, such as sinus thrombosis or cerebral infarction, might also have caused MSICH. MSICH can occur as a fatal complication of COVID-19, and this should be considered when providing treatment.
Keywords: COVID-19; ECMO; SARS-CoV-2; anticoagulant; hypercoagulability; intracerebral hemorrhage.
. 2020 Sep 5.
doi: 10.2169/internalmedicine.5697-20. Online ahead of print.
Coronavirus Disease 2019 Complicated by Multiple Simultaneous Intracerebral Hemorrhages
Ryota Motoie[SUP] 1 [/SUP], Masaya Akai[SUP] 2 [/SUP], Takahiro Kitahara[SUP] 1 [/SUP], Hisaji Imamura[SUP] 3 [/SUP], Takeshi Tanabe[SUP] 4 [/SUP], Katsuhiko Sarazawa[SUP] 5 [/SUP], Seiichiro Takano[SUP] 3 [/SUP], Hiroki Toda[SUP] 1 [/SUP], Kazuto Komatsu[SUP] 6 [/SUP]
Affiliations
- PMID: 32893231
- DOI: 10.2169/internalmedicine.5697-20
Abstract
The relationship between coronavirus disease 2019 (COVID-19) and intracerebral hemorrhage remains unclear. We herein report a case of severe COVID-19 pneumonia complicated by multiple simultaneous intracerebral hemorrhages (MSICH). The patient died eight days after the episode of MSICH. No apparent coagulopathy was observed; however, extracorporeal membrane oxygenation and anticoagulation might have caused the occurrence of MSICH. Laboratory findings showed hypercoagulability, suggesting that thrombotic etiologies, such as sinus thrombosis or cerebral infarction, might also have caused MSICH. MSICH can occur as a fatal complication of COVID-19, and this should be considered when providing treatment.
Keywords: COVID-19; ECMO; SARS-CoV-2; anticoagulant; hypercoagulability; intracerebral hemorrhage.