tetano
Editor, Senior Moderator
Intern Med
. 2022 Sep 6.
doi: 10.2169/internalmedicine.9410-22. Online ahead of print.
Crescentic Glomerulonephritis with Fibrinoid Vasculitis after Administration of Influenza Vaccine: A Case Report
Risa Hara[SUP] 1 [/SUP], Eiko Hasegawa[SUP] 1 [/SUP], Noriko Inoue[SUP] 1 [/SUP], Akinari Sekine[SUP] 1 [/SUP], Kiho Tanaka[SUP] 1 [/SUP], Daisuke Ikuma[SUP] 1 [/SUP], Hiroki Mizuno[SUP] 1 [/SUP], Yuki Oba[SUP] 1 [/SUP], Masayuki Yamanouchi[SUP] 1 [/SUP], Tatsuya Suwabe[SUP] 1 [/SUP], Naoki Sawa[SUP] 1 2 [/SUP], Kei Kono[SUP] 3 [/SUP], Keiichi Kinowaki[SUP] 3 [/SUP], Kenichi Ohashi[SUP] 3 2 [/SUP], Yoshifumi Ubara[SUP] 1 [/SUP], Junichi Hoshino[SUP] 1 [/SUP]
Affiliations
Abstract
A 66-year-old man was admitted to our hospital because of a low-grade fever and arthralgia. The symptoms started on the third day after influenza vaccine administration and persisted for two months. Serum creatinine was 1.0 mg/dL; CRP, 16.1 mg/dL; and MPO-ANCA, 4,170 IU/mL. A kidney biopsy showed crescentic glomerulonephritis with fibrinoid necrosis of small arteries. Microscopic polyangiitis was diagnosed. After five months of steroid pulse therapy and rituximab administration, the patient entered remission. There have been very few reports of this condition after influenza vaccine administration.
Keywords: ANCA-associated vasculitis; influenza vaccine; microscopic polyangiitis.
. 2022 Sep 6.
doi: 10.2169/internalmedicine.9410-22. Online ahead of print.
Crescentic Glomerulonephritis with Fibrinoid Vasculitis after Administration of Influenza Vaccine: A Case Report
Risa Hara[SUP] 1 [/SUP], Eiko Hasegawa[SUP] 1 [/SUP], Noriko Inoue[SUP] 1 [/SUP], Akinari Sekine[SUP] 1 [/SUP], Kiho Tanaka[SUP] 1 [/SUP], Daisuke Ikuma[SUP] 1 [/SUP], Hiroki Mizuno[SUP] 1 [/SUP], Yuki Oba[SUP] 1 [/SUP], Masayuki Yamanouchi[SUP] 1 [/SUP], Tatsuya Suwabe[SUP] 1 [/SUP], Naoki Sawa[SUP] 1 2 [/SUP], Kei Kono[SUP] 3 [/SUP], Keiichi Kinowaki[SUP] 3 [/SUP], Kenichi Ohashi[SUP] 3 2 [/SUP], Yoshifumi Ubara[SUP] 1 [/SUP], Junichi Hoshino[SUP] 1 [/SUP]
Affiliations
- PMID: 36070955
- DOI: 10.2169/internalmedicine.9410-22
Abstract
A 66-year-old man was admitted to our hospital because of a low-grade fever and arthralgia. The symptoms started on the third day after influenza vaccine administration and persisted for two months. Serum creatinine was 1.0 mg/dL; CRP, 16.1 mg/dL; and MPO-ANCA, 4,170 IU/mL. A kidney biopsy showed crescentic glomerulonephritis with fibrinoid necrosis of small arteries. Microscopic polyangiitis was diagnosed. After five months of steroid pulse therapy and rituximab administration, the patient entered remission. There have been very few reports of this condition after influenza vaccine administration.
Keywords: ANCA-associated vasculitis; influenza vaccine; microscopic polyangiitis.