tetano
Editor, Senior Moderator
J Virol. 2015 Apr 8. pii: JVI.00462-15. [Epub ahead of print]
[h=1]Investigating Influenza A virus infection: Tools to track infection and tropism.[/h] Fiege JK[SUP]1[/SUP], Langlois RA[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza A viruses display a broad cellular tropism within the reparatory tract of mammalian hosts. Uncovering the relationship between tropism and virus immunity, pathogenesis, and transmission will be critical for the development of therapeutic interventions. Here we discuss recent developments of several recombinant strains of influenza A virus. These viruses have inserted reporters to track tropism, microRNA target sites to restrict tropism or barcodes to assess transmission dynamics, expanding our understanding of pathogen host interactions.
Copyright ? 2015, American Society for Microbiology. All Rights Reserved.
PMID: 25855737 [PubMed - as supplied by publisher]
[h=1]Investigating Influenza A virus infection: Tools to track infection and tropism.[/h] Fiege JK[SUP]1[/SUP], Langlois RA[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza A viruses display a broad cellular tropism within the reparatory tract of mammalian hosts. Uncovering the relationship between tropism and virus immunity, pathogenesis, and transmission will be critical for the development of therapeutic interventions. Here we discuss recent developments of several recombinant strains of influenza A virus. These viruses have inserted reporters to track tropism, microRNA target sites to restrict tropism or barcodes to assess transmission dynamics, expanding our understanding of pathogen host interactions.
Copyright ? 2015, American Society for Microbiology. All Rights Reserved.
PMID: 25855737 [PubMed - as supplied by publisher]