tetano
Editor, Senior Moderator
iScience
. 2021 Feb 12;102188.
doi: 10.1016/j.isci.2021.102188. Online ahead of print.
Pre-existing conditions in Hispanics/Latinxs that are COVID-19 risk factors
Timothy S Chang[SUP] 1 [/SUP], Yi Ding[SUP] 2 3 [/SUP], Malika K Freund[SUP] 3 4 [/SUP], Ruth Johnson[SUP] 3 5 [/SUP], Tommer Schwarz[SUP] 2 3 [/SUP], Julie M Yabu[SUP] 6 [/SUP], Chad Hazlett[SUP] 7 8 [/SUP], Jeffrey N Chiang[SUP] 9 [/SUP], David A Wulf[SUP] 7 [/SUP], UCLA Precision Health Data Discovery Repository Working Group; Daniel H Geschwind[SUP] 1 4 10 [/SUP], Manish J Butte[SUP] 11 12 [/SUP], Bogdan Pasaniuc[SUP] 2 3 4 9 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) has exposed health care disparities in minority groups including Hispanics/Latinxs (HL). Studies of COVID-19 risk factors for HL have relied on county-level data. We investigated COVID-19 risk factors in HL using individual-level, electronic health records in a Los Angeles health system between March 9 and August 31, 2020. Of 9,287 HL tested for SARS-CoV-2, 562 were positive. HL constituted an increasing percentage of all COVID-19 positive individuals as disease severity escalated. Multiple risk factors identified in Non-Hispanic/Latinx whites (NHL-W), like renal disease, also conveyed risk in HL. Pre-existing nonrheumatic mitral valve disorder was a risk factor to HL hospitalization but not for NHL-W COVID-19 or HL influenza hospitalization, suggesting it may be a specific HL COVID-19 risk. Admission laboratory values also suggested that HL presented with a greater inflammatory response. COVID-19 risk factors for HL can help guide equitable government policies and identify at-risk populations.
. 2021 Feb 12;102188.
doi: 10.1016/j.isci.2021.102188. Online ahead of print.
Pre-existing conditions in Hispanics/Latinxs that are COVID-19 risk factors
Timothy S Chang[SUP] 1 [/SUP], Yi Ding[SUP] 2 3 [/SUP], Malika K Freund[SUP] 3 4 [/SUP], Ruth Johnson[SUP] 3 5 [/SUP], Tommer Schwarz[SUP] 2 3 [/SUP], Julie M Yabu[SUP] 6 [/SUP], Chad Hazlett[SUP] 7 8 [/SUP], Jeffrey N Chiang[SUP] 9 [/SUP], David A Wulf[SUP] 7 [/SUP], UCLA Precision Health Data Discovery Repository Working Group; Daniel H Geschwind[SUP] 1 4 10 [/SUP], Manish J Butte[SUP] 11 12 [/SUP], Bogdan Pasaniuc[SUP] 2 3 4 9 [/SUP]
Affiliations
- PMID: 33615196
- PMCID: PMC7879099
- DOI: 10.1016/j.isci.2021.102188
Abstract
Coronavirus disease 2019 (COVID-19) has exposed health care disparities in minority groups including Hispanics/Latinxs (HL). Studies of COVID-19 risk factors for HL have relied on county-level data. We investigated COVID-19 risk factors in HL using individual-level, electronic health records in a Los Angeles health system between March 9 and August 31, 2020. Of 9,287 HL tested for SARS-CoV-2, 562 were positive. HL constituted an increasing percentage of all COVID-19 positive individuals as disease severity escalated. Multiple risk factors identified in Non-Hispanic/Latinx whites (NHL-W), like renal disease, also conveyed risk in HL. Pre-existing nonrheumatic mitral valve disorder was a risk factor to HL hospitalization but not for NHL-W COVID-19 or HL influenza hospitalization, suggesting it may be a specific HL COVID-19 risk. Admission laboratory values also suggested that HL presented with a greater inflammatory response. COVID-19 risk factors for HL can help guide equitable government policies and identify at-risk populations.