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Isolation and molecular characterization of reassortant H11N3 subtype avian influenza viruses isolated from domestic ducks in Zhejiang Province in Chi

tetano

Editor, Senior Moderator
Virus Genes. 2016 May 3. [Epub ahead of print]
[h=1]Isolation and molecular characterization of reassortant H11N3 subtype avian influenza viruses isolated from domestic ducks in Zhejiang Province in China.[/h] Wu H[SUP]1[/SUP], Peng X[SUP]2[/SUP], Peng X[SUP]2[/SUP], Wu N[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] In July 2013, six H11N3 subtype avian influenza viruses (AIVs) were isolated from domestic ducks in Zhejiang Province in Eastern China. These strains were characterized by whole genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that these strains clustered in the AIV Eurasian lineage, and these strains received their genes from H11, H7, and H1 AIVs in Eastern China. These strains were found to be minimally pathogenic in mice, and were able to replicate in mice without prior adaptation. Continued surveillance is needed considering the important role of domestic ducks in AIV reassortment.


[h=4]KEYWORDS:[/h] Avian influenza viruses; Domestic ducks; Reassortment; Subtype H11N3

PMID: 27142079 [PubMed - as supplied by publisher]
 
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