tetano
Editor, Senior Moderator
Isr Med Assoc J
. 2023 Jun;25(6):387-391.
Clinical Outcomes and Laboratory Values of Infants with COVID-19 among Several Maternal Variables: A Retrospective Cohort
Tal Bechor Ariel[SUP] 1 [/SUP], Ben Ariel[SUP] 1 [/SUP], Yuni Lahav[SUP] 1 [/SUP], Moshe Yana[SUP] 1 [/SUP], Michael Ben-Acon[SUP] 1 [/SUP], Nechama Sharon[SUP] 1 [/SUP]
Affiliations
Background: Infants younger than 6 months of age are not eligible for coronavirus disease 2019 (COVID-19) vaccinations. Maternal variables during pregnancy and the postnatal period may affect the clinical and laboratory course of COVID-19 positive infants.
Objectives: To assess the clinical manifestation and laboratory differences in infants with three maternal variables: breastfeeding, vaccinated, and co-illness.
Methods: We conducted a single-center retrospective cohort study of positive COVID-19 infants with three subgroups of maternal variables. The population included infants under 6 months of age hospitalized due to COVID-19. Data about clinical features, laboratory tests, and maternal information including vaccination status, breastfeeding status and maternal positive COVID-19 infection was gathered. All variables were compared among the three subgroups.
Results: Breastfed infants had shorter hospitalization period (mean 2.61 ± 1.378 days) compared to non-breastfed infants (mean 3.8 ± 1.549) (P = 0.051). COVID-19 infants of positive COVID-19 mothers had a higher absolute neutrophil count (mean 4.4 ± 3.8) compared to infants of COVID-19 negative mothers (mean 2.7 ± 2.4) (P = 0.042).
Conclusions: Breastfeeding was associated with shorter periods of hospitalization in COVID-19 positive infants. In addition, positive COVID-19 infants of mothers who were positive for COVID-19 are likely to have a higher absolute neutrophils count.
. 2023 Jun;25(6):387-391.
Clinical Outcomes and Laboratory Values of Infants with COVID-19 among Several Maternal Variables: A Retrospective Cohort
Tal Bechor Ariel[SUP] 1 [/SUP], Ben Ariel[SUP] 1 [/SUP], Yuni Lahav[SUP] 1 [/SUP], Moshe Yana[SUP] 1 [/SUP], Michael Ben-Acon[SUP] 1 [/SUP], Nechama Sharon[SUP] 1 [/SUP]
Affiliations
- PMID: 37381930
Background: Infants younger than 6 months of age are not eligible for coronavirus disease 2019 (COVID-19) vaccinations. Maternal variables during pregnancy and the postnatal period may affect the clinical and laboratory course of COVID-19 positive infants.
Objectives: To assess the clinical manifestation and laboratory differences in infants with three maternal variables: breastfeeding, vaccinated, and co-illness.
Methods: We conducted a single-center retrospective cohort study of positive COVID-19 infants with three subgroups of maternal variables. The population included infants under 6 months of age hospitalized due to COVID-19. Data about clinical features, laboratory tests, and maternal information including vaccination status, breastfeeding status and maternal positive COVID-19 infection was gathered. All variables were compared among the three subgroups.
Results: Breastfed infants had shorter hospitalization period (mean 2.61 ± 1.378 days) compared to non-breastfed infants (mean 3.8 ± 1.549) (P = 0.051). COVID-19 infants of positive COVID-19 mothers had a higher absolute neutrophil count (mean 4.4 ± 3.8) compared to infants of COVID-19 negative mothers (mean 2.7 ± 2.4) (P = 0.042).
Conclusions: Breastfeeding was associated with shorter periods of hospitalization in COVID-19 positive infants. In addition, positive COVID-19 infants of mothers who were positive for COVID-19 are likely to have a higher absolute neutrophils count.