tetano
Editor, Senior Moderator
J Allergy Clin Immunol Pract
. 2020 Jun 16;S2213-2198(20)30599-7.
doi: 10.1016/j.jaip.2020.06.001. Online ahead of print.
Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden
Nikolaos G Papadopoulos[SUP] 1 [/SUP], Adnan Custovic[SUP] 2 [/SUP], Antoine Deschildre[SUP] 3 [/SUP], Alexander G Mathioudakis[SUP] 4 [/SUP], Wanda Phipatanakul[SUP] 5 [/SUP], Gary Wong[SUP] 6 [/SUP], Paraskevi Xepapadaki[SUP] 7 [/SUP], Ioana Agache[SUP] 8 [/SUP], Leonard Bacharier[SUP] 9 [/SUP], Matteo Bonini[SUP] 10 [/SUP], Jose A Castro-Rodriguez[SUP] 11 [/SUP], Zhimin Chen[SUP] 12 [/SUP], Timothy Craig[SUP] 13 [/SUP], Francine M Ducharme[SUP] 14 [/SUP], Zeinab Awad El-Sayed[SUP] 15 [/SUP], Wojciech Feleszko[SUP] 16 [/SUP], Alessandro Fiocci[SUP] 17 [/SUP], Luis Garcia-Marcos[SUP] 18 [/SUP], James E Gern[SUP] 19 [/SUP], Anne Goh[SUP] 20 [/SUP], Ren? Maximiliano G?mez[SUP] 21 [/SUP], Eckard H Hamelmann[SUP] 22 [/SUP], Gunilla Hedlin[SUP] 23 [/SUP], Elham M Hossny[SUP] 15 [/SUP], Tuomas Jartti[SUP] 24 [/SUP], Omer Kalayci[SUP] 25 [/SUP], Alan Kaplan[SUP] 26 [/SUP], Jon Konrandsen[SUP] 27 [/SUP], Piotr Kuna[SUP] 28 [/SUP], Susanne Lau[SUP] 29 [/SUP], Peter Le Souef[SUP] 30 [/SUP], Robert F Lemanske[SUP] 31 [/SUP], Mika J Makela[SUP] 32 [/SUP], M?rio Morais-Almeida[SUP] 33 [/SUP], Clare Murray[SUP] 34 [/SUP], Karthik Nagaraju[SUP] 35 [/SUP], Leyla Namazova-Baranova[SUP] 36 [/SUP], Antonio Nieto Garcia[SUP] 37 [/SUP], Yusuf Osman[SUP] 38 [/SUP], Paulo Mc Pitrez[SUP] 39 [/SUP], Petr Pohunek[SUP] 40 [/SUP], Cesar Fireth Pozo Beltr?n[SUP] 41 [/SUP], Graham C Roberts[SUP] 42 [/SUP], Arunas Valiulis[SUP] 43 [/SUP], Heather J Zar[SUP] 44 [/SUP], PeARL collaborators
Affiliations
Abstract
Background: It is unclear whether asthma may affect susceptibility or severity of the Coronavirus Disease 2019 (COVID-19) in children and how pediatric asthma services worldwide have responded to the pandemic.
Objective: To describe the impact of the COVID-19 pandemic on pediatric asthma services and on disease burden in their patients.
Methods: An online survey was sent to members of the Pediatric Asthma in Real Life (PeARL) think-tank and the World Allergy Organization Pediatric Asthma Committee. It included questions on service provision, disease burden and on the clinical course of confirmed cases of COVID-19 infection among children with asthma.
Results: Ninety-one respondents, caring for an estimated population of >133,000 children with asthma, completed the survey. COVID-19 significantly impacted pediatric asthma services: 39% ceased physical appointments, 47% stopped accepting new patients, 75% limited patients visits. Consultations were almost halved to a median of 20 (IQR: 10-25) patients per week. Virtual clinics and helplines were launched in most centers. Better than expected disease control was reported in 20% (10-40%) of patients, while control was negatively affected in only 10% (7.5-12.5%). Adherence also appeared to increase. Only 15 confirmed cases of COVID-19 were reported among the population; the estimated incidence is not apparently different from the reports of general pediatric cohorts.
Conclusion: Children with asthma do not appear to be disproportionately affected by COVID-19. Outcomes may even have improved, possibly through increased adherence and/or reduced exposures. Clinical services have rapidly responded to the pandemic by limiting and replacing physical appointments with virtual encounters.
Keywords: COVID-19; SARS-CoV2; adherence; asthma; child; control; virus.
. 2020 Jun 16;S2213-2198(20)30599-7.
doi: 10.1016/j.jaip.2020.06.001. Online ahead of print.
Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden
Nikolaos G Papadopoulos[SUP] 1 [/SUP], Adnan Custovic[SUP] 2 [/SUP], Antoine Deschildre[SUP] 3 [/SUP], Alexander G Mathioudakis[SUP] 4 [/SUP], Wanda Phipatanakul[SUP] 5 [/SUP], Gary Wong[SUP] 6 [/SUP], Paraskevi Xepapadaki[SUP] 7 [/SUP], Ioana Agache[SUP] 8 [/SUP], Leonard Bacharier[SUP] 9 [/SUP], Matteo Bonini[SUP] 10 [/SUP], Jose A Castro-Rodriguez[SUP] 11 [/SUP], Zhimin Chen[SUP] 12 [/SUP], Timothy Craig[SUP] 13 [/SUP], Francine M Ducharme[SUP] 14 [/SUP], Zeinab Awad El-Sayed[SUP] 15 [/SUP], Wojciech Feleszko[SUP] 16 [/SUP], Alessandro Fiocci[SUP] 17 [/SUP], Luis Garcia-Marcos[SUP] 18 [/SUP], James E Gern[SUP] 19 [/SUP], Anne Goh[SUP] 20 [/SUP], Ren? Maximiliano G?mez[SUP] 21 [/SUP], Eckard H Hamelmann[SUP] 22 [/SUP], Gunilla Hedlin[SUP] 23 [/SUP], Elham M Hossny[SUP] 15 [/SUP], Tuomas Jartti[SUP] 24 [/SUP], Omer Kalayci[SUP] 25 [/SUP], Alan Kaplan[SUP] 26 [/SUP], Jon Konrandsen[SUP] 27 [/SUP], Piotr Kuna[SUP] 28 [/SUP], Susanne Lau[SUP] 29 [/SUP], Peter Le Souef[SUP] 30 [/SUP], Robert F Lemanske[SUP] 31 [/SUP], Mika J Makela[SUP] 32 [/SUP], M?rio Morais-Almeida[SUP] 33 [/SUP], Clare Murray[SUP] 34 [/SUP], Karthik Nagaraju[SUP] 35 [/SUP], Leyla Namazova-Baranova[SUP] 36 [/SUP], Antonio Nieto Garcia[SUP] 37 [/SUP], Yusuf Osman[SUP] 38 [/SUP], Paulo Mc Pitrez[SUP] 39 [/SUP], Petr Pohunek[SUP] 40 [/SUP], Cesar Fireth Pozo Beltr?n[SUP] 41 [/SUP], Graham C Roberts[SUP] 42 [/SUP], Arunas Valiulis[SUP] 43 [/SUP], Heather J Zar[SUP] 44 [/SUP], PeARL collaborators
Affiliations
- PMID: 32561497
- DOI: 10.1016/j.jaip.2020.06.001
Abstract
Background: It is unclear whether asthma may affect susceptibility or severity of the Coronavirus Disease 2019 (COVID-19) in children and how pediatric asthma services worldwide have responded to the pandemic.
Objective: To describe the impact of the COVID-19 pandemic on pediatric asthma services and on disease burden in their patients.
Methods: An online survey was sent to members of the Pediatric Asthma in Real Life (PeARL) think-tank and the World Allergy Organization Pediatric Asthma Committee. It included questions on service provision, disease burden and on the clinical course of confirmed cases of COVID-19 infection among children with asthma.
Results: Ninety-one respondents, caring for an estimated population of >133,000 children with asthma, completed the survey. COVID-19 significantly impacted pediatric asthma services: 39% ceased physical appointments, 47% stopped accepting new patients, 75% limited patients visits. Consultations were almost halved to a median of 20 (IQR: 10-25) patients per week. Virtual clinics and helplines were launched in most centers. Better than expected disease control was reported in 20% (10-40%) of patients, while control was negatively affected in only 10% (7.5-12.5%). Adherence also appeared to increase. Only 15 confirmed cases of COVID-19 were reported among the population; the estimated incidence is not apparently different from the reports of general pediatric cohorts.
Conclusion: Children with asthma do not appear to be disproportionately affected by COVID-19. Outcomes may even have improved, possibly through increased adherence and/or reduced exposures. Clinical services have rapidly responded to the pandemic by limiting and replacing physical appointments with virtual encounters.
Keywords: COVID-19; SARS-CoV2; adherence; asthma; child; control; virus.