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J Am Coll Emerg Physicians Open . Immune thrombocytopenia in 2 healthy young women after the Pfizer-BioNTech BNT16B2b2 messenger RNA coronavirus di

tetano

Editor, Senior Moderator
J Am Coll Emerg Physicians Open


. 2021 Sep 17;2(5):e12531.
doi: 10.1002/emp2.12531. eCollection 2021 Oct.
Immune thrombocytopenia in 2 healthy young women after the Pfizer-BioNTech BNT16B2b2 messenger RNA coronavirus disease 2019 vaccination


Emilie C Collins[SUP] 1 [/SUP], Michael J Carr[SUP] 1 [/SUP], James Soo Kim[SUP] 2 [/SUP], John Lewis Jr[SUP] 1 [/SUP], Noble Maleque[SUP] 3 [/SUP], Krisha Desai[SUP] 3 [/SUP], Lauren Chen[SUP] 3 [/SUP], Jon Sevransky[SUP] 4 [/SUP], Manila Gaddh[SUP] 5 [/SUP], Nadine Rouphael[SUP] 6 [/SUP], Jacqueline Hubbard[SUP] 7 [/SUP], Andrew M Pendley[SUP] 8 [/SUP]



Affiliations
Free PMC article

Abstract

Immune thrombocytopenic purpura (ITP) is a rare complication associated with vaccines targeting various diseases, including influenza, measles-mumps-rubella, hepatitis B, and diphtheria-tetanus-pertussis. We report 2 cases of ITP in healthy 20-year-old and 21-year-old women presenting to Emory University in Atlanta, GA, 2 days after the second dose and 11 days after the first dose (respectively) of the Pfizer-BioNTech messenger RNA severe acute respiratory syndrome coronavirus 2 vaccine. Both patients recovered quickly. With more than a billion doses of coronavirus disease 2019 vaccines safely administered worldwide as of May 2021, discussions with patients should put into perspective the low risks of vaccination against the enormous societal benefit of the coronavirus disease 2019 vaccine.

Keywords: ITP; coronavirus disease 2019 vaccine; thrombocytopenia.
 
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