tetano
Editor, Senior Moderator
J Anesth
. 2020 Aug 31.
doi: 10.1007/s00540-020-02845-0. Online ahead of print.
Respiratory characteristics and related intraoperative ventilatory management for patients with COVID-19 pneumonia
Hiroko Aoyama[SUP] 1 [/SUP], Kanji Uchida[SUP] 2 [/SUP]
Affiliations
Abstract
A substantial proportion of patients with coronavirus disease 19 (COVID-19) develop severe respiratory failure. Although the exact pathophysiology of severe COVID-19 pneumonia remains unknown and the characteristics of these patients are heterogeneous, the acute respiratory failure often fulfills criteria for acute respiratory distress syndrome (ARDS) and the clinical characteristics are also consistent with what is previously known about ARDS. Cohort studies also report distinctively high association between perioperative COVID-19 and postoperative mortality. In this special article, we review several publications on the pathophysiology of COVID-19, and discuss intraoperative ventilatory management for patients with COVID-19 based on the respiratory characteristics of COVID-19 pneumonia in light of the ongoing controversy of clinical phenotypes.
Keywords: COVID-19; Intraoperative management; Phenotype; Respiratory characteristics; SARS-CoV-2.
. 2020 Aug 31.
doi: 10.1007/s00540-020-02845-0. Online ahead of print.
Respiratory characteristics and related intraoperative ventilatory management for patients with COVID-19 pneumonia
Hiroko Aoyama[SUP] 1 [/SUP], Kanji Uchida[SUP] 2 [/SUP]
Affiliations
- PMID: 32865700
- DOI: 10.1007/s00540-020-02845-0
Abstract
A substantial proportion of patients with coronavirus disease 19 (COVID-19) develop severe respiratory failure. Although the exact pathophysiology of severe COVID-19 pneumonia remains unknown and the characteristics of these patients are heterogeneous, the acute respiratory failure often fulfills criteria for acute respiratory distress syndrome (ARDS) and the clinical characteristics are also consistent with what is previously known about ARDS. Cohort studies also report distinctively high association between perioperative COVID-19 and postoperative mortality. In this special article, we review several publications on the pathophysiology of COVID-19, and discuss intraoperative ventilatory management for patients with COVID-19 based on the respiratory characteristics of COVID-19 pneumonia in light of the ongoing controversy of clinical phenotypes.
Keywords: COVID-19; Intraoperative management; Phenotype; Respiratory characteristics; SARS-CoV-2.