tetano
Editor, Senior Moderator
J Cardiol Cases
. 2022 Feb 11.
doi: 10.1016/j.jccase.2022.01.015. Online ahead of print.
Cardiac magnetic resonance findings in acute myocarditis after mRNA COVID-19 vaccination
Madoka Sano[SUP] 1 [/SUP], Ryosuke Murai[SUP] 1 [/SUP], Kitae Kim[SUP] 1 [/SUP], Yutaka Furukawa[SUP] 1 [/SUP]
Affiliations
Abstract
There is increasing evidence for myocarditis as a complication of the mRNA coronavirus disease 2019 (COVID-19) vaccination. We report the case of a 20-year-old previously healthy man who presented with fever and chest pain 2 days after the second dose of mRNA-1273 vaccine. Electrocardiogram and laboratory studies showed extensive ST-segment elevation accompanied by elevated cardiac biomarkers. Cardiac magnetic resonance (CMR) revealed late gadolinium enhancement (LGE) characteristics of myocarditis. The patient rapidly improved with conservative management and was discharged on hospital day 6. As an advantage over previous reports, we performed a 1-month follow-up CMR. It showed improvement in myocardial edema but persistence of LGE which may indicate irreversible fibrosis. CMR may be useful not only for diagnosis but also for prognostic evaluation of myocarditis after COVID-19 mRNA vaccination.
Keywords: Acute myocarditis; Coronavirus disease 2019; mRNA vaccination.
. 2022 Feb 11.
doi: 10.1016/j.jccase.2022.01.015. Online ahead of print.
Cardiac magnetic resonance findings in acute myocarditis after mRNA COVID-19 vaccination
Madoka Sano[SUP] 1 [/SUP], Ryosuke Murai[SUP] 1 [/SUP], Kitae Kim[SUP] 1 [/SUP], Yutaka Furukawa[SUP] 1 [/SUP]
Affiliations
- PMID: 35169401
- PMCID: PMC8831126
- DOI: 10.1016/j.jccase.2022.01.015
Abstract
There is increasing evidence for myocarditis as a complication of the mRNA coronavirus disease 2019 (COVID-19) vaccination. We report the case of a 20-year-old previously healthy man who presented with fever and chest pain 2 days after the second dose of mRNA-1273 vaccine. Electrocardiogram and laboratory studies showed extensive ST-segment elevation accompanied by elevated cardiac biomarkers. Cardiac magnetic resonance (CMR) revealed late gadolinium enhancement (LGE) characteristics of myocarditis. The patient rapidly improved with conservative management and was discharged on hospital day 6. As an advantage over previous reports, we performed a 1-month follow-up CMR. It showed improvement in myocardial edema but persistence of LGE which may indicate irreversible fibrosis. CMR may be useful not only for diagnosis but also for prognostic evaluation of myocarditis after COVID-19 mRNA vaccination.
Keywords: Acute myocarditis; Coronavirus disease 2019; mRNA vaccination.